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Prostate drug offers new relief for kidney stone sufferers

Clinical trial patients pass large kidney stones with the drug Tamsulosin

Date:
November 2, 2016
Source:
Emergency Medicine Foundation (Australia)
Summary:
A prostrate treatment can also help ease the pain of passing kidney stones, new research suggests. One in 11 people in the United States suffer from kidney stones, which range in size from a grain of sand to a pearl or even larger, and can be excruciating to pass through the urinary tract.
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Millions of Australians suffering from kidney stones could soon get relief, with researchers discovering a prostrate treatment can also help ease the painful condition.

Patients with kidney stones were treated with the drug Tamsulosin in an Emergency Medicine Foundation Australasia (EMF) funded clinical trial run across five Australian hospital emergency departments.

Trial leader and specialist emergency medicine physician at The Townsville Hospital, Dr Jeremy Furyk, said Tamsulosin was normally used to treat an enlarged prostate, but the research team found the treatment could also assist the passage of large kidney stones in the urine.

"Kidney stones are a bit of a mystery, occur frequently in the community and generally affect young, healthy adults," Dr Furyk said.

"It can be extremely painful to pass these jagged little crystallized minerals and it's very common for sufferers to go to an emergency department for treatment.

"Of more than 400 patients in the trial, we found those who received Tamsulosin passed their large kidney stones more often than the placebo group.

"This means patients with large stones might not need more complicated treatments including surgeries, and this has potential to improve care and reduce costs. We're very excited because Tamsulosin treatment may also allow patients to be treated closer to home rather than needing referral to a major centre."

EMF Australasia awarded more than $270,000 to support Dr Furyk's research, through its Queensland Research Program, which is funded by the Queensland Government Department of Health.

EMF Australasia Chair, Associate Professor Sally McCarthy said this research had the potential to help millions of Australians suffering with this extremely painful condition.

"It may also have implications for patients living in rural and regional areas, where access to urologists -- the specialist doctors who treat this condition -- can be limited."

Up to 15 per cent of the Australian adult population and 1 in 11 people in the United States suffer from kidney stones, which range in size from a grain of sand to a pearl or even larger, and can be excruciating to pass through the urinary tract.


Story Source:

Materials provided by Emergency Medicine Foundation (Australia). Note: Content may be edited for style and length.


Journal Reference:

  1. Ralph C. Wang, Rebecca Smith-Bindman, Evans Whitaker, Jersey Neilson, Isabel Elaine Allen, Marshall L. Stoller, Jahan Fahimi. Effect of Tamsulosin on Stone Passage for Ureteral Stones: A Systematic Review and Meta-analysis. Annals of Emergency Medicine, 2016; DOI: 10.1016/j.annemergmed.2016.06.044

Cite This Page:

Emergency Medicine Foundation (Australia). "Prostate drug offers new relief for kidney stone sufferers: Clinical trial patients pass large kidney stones with the drug Tamsulosin." ScienceDaily. ScienceDaily, 2 November 2016. <www.sciencedaily.com/releases/2016/11/161102143508.htm>.
Emergency Medicine Foundation (Australia). (2016, November 2). Prostate drug offers new relief for kidney stone sufferers: Clinical trial patients pass large kidney stones with the drug Tamsulosin. ScienceDaily. Retrieved May 27, 2017 from www.sciencedaily.com/releases/2016/11/161102143508.htm
Emergency Medicine Foundation (Australia). "Prostate drug offers new relief for kidney stone sufferers: Clinical trial patients pass large kidney stones with the drug Tamsulosin." ScienceDaily. www.sciencedaily.com/releases/2016/11/161102143508.htm (accessed May 27, 2017).

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