Science News
from research organizations

Preparation of food grade capsules for targeted drug delivery

Date:
March 12, 2015
Source:
The Hong Kong Polytechnic University
Summary:
A novel capsule has been designed with zein and pectin by taking the advantage of the substances' unique physicochemical properties. Zein is a major corn protein, while pectin is a gelforming polysaccharide obtained from most citrus fruits. In this specially designed capsule, zein acts as a water barrier to protect pectin from swelling while pectin protects zein from intestinal digestion. More importantly, by varying the ratio of these two materials and modifying the capsule design, targeted drug delivery either to the stomach, the small intestine or the colon can be achieved.
Share:
FULL STORY

Researchers at Hong Kong Polytechnic University have developed a novel capsule with zein and pectin by taking the advantage of the substances' unique physicochemical properties.

Nowadays capsules are commonly made of synthetic polymers or animal derived gelatin, which are of great safety and health concerns. We used zein and pectin to prepare a novel capsule by taking advantages of their unique physicochemical properties.

Zein is a major corn protein, while pectin is a gelforming polysaccharide obtained from most citrus fruits. In this specially designed capsule, zein acts as a water barrier to protect pectin from swelling while pectin protects zein from intestinal digestion. More importantly, by varying the ratio of these two materials and modifying the capsule design, targeted drug delivery either to the stomach, the small intestine or the colon can be achieved.

Special Features and Advantages:

• The capsule materials used are food-grade, plant-based and under-utilised byproducts. Thus, they are safe, fit for vegetarians and inexpensive

• Suitable for both drug and health food industries

• Gold Medal -- 42nd International Exhibition of Inventions of Geneva, Switzerland (April 2014)


Story Source:

Materials provided by The Hong Kong Polytechnic University. Note: Content may be edited for style and length.


Cite This Page:

The Hong Kong Polytechnic University. "Preparation of food grade capsules for targeted drug delivery." ScienceDaily. ScienceDaily, 12 March 2015. <www.sciencedaily.com/releases/2015/03/150312142516.htm>.
The Hong Kong Polytechnic University. (2015, March 12). Preparation of food grade capsules for targeted drug delivery. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2015/03/150312142516.htm
The Hong Kong Polytechnic University. "Preparation of food grade capsules for targeted drug delivery." ScienceDaily. www.sciencedaily.com/releases/2015/03/150312142516.htm (accessed May 23, 2017).

RELATED STORIES