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Tracking Down The Cause Of Mad Cow Disease: First Synthetic Prion Protein With An Anchor
Researchers in Germany and
Switzerland have developed a
new general method for the
synthesis of anchored
proteins, such as
... > full story
How Small Molecule Can Take Apart Alzheimer's Disease Protein Fibers
Researchers have shown, in
unprecedented detail, how a
small molecule is able to
selectively take apart
abnormally folded protein
fibers connected to
... > full story
Scientists Find New Causes For Neurodegeneration
Diseases that cause neurons
to break down, such as
Alzheimer's, continue to be
elusive to scientists and
resistant to treatments. A
new finding demonstrates an
... > full story
Prions May Activate Retroviruses In Infected Brain Cells
Prion proteins may activate
endogenous retroviruses in
infected brain cells. Prions
– an abbreviation for
proteinaceous infectious
particles – work as a
... > full story
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Mad Cow And Related Diseases: Copper Linked To Normal Functioning Of Prions
June 28, 2009 — Researchers have discovered a link between copper and the normal functioning of prion proteins, which are associated with transmissible spongiform encephalopathy diseases such as Cruetzfeldt-Jakob in ... > full story -
How Prion Protein Damages Brain Cells: Findings Could Advance Understanding Of Mad Cow Disease, Related Disorders
June 15, 2009 — Scientists have gained a major insight into how the rogue protein responsible for mad cow disease and related neurological illnesses destroys healthy brain ... > full story -
Iron Is Involved In Prion Disease-associated Neuronal Demise
March 20, 2009 — Imbalance of iron homeostasis is a common feature of prion disease-affected human, mouse, and hamster brains, according to a new study. These findings provide new insight into the mechanism of ... > full story -
Mad Cow Disease
Brain Tumor
Brain Injury
Disorders and Syndromes
Stroke Prevention
Diseases and Conditions
Antibody Key To Treating Variant Creutzfeldt-Jakob Disease (vCJD)
March 12, 2009 — Scientists have determined the atomic structure of the "binding" between a brain protein and an antibody that could be key to treating patients with diseases such as variant ... > full story -
New Piece In Alzheimer's Puzzle
February 27, 2009 — Researchers have filled in a missing gap on the molecular road map of Alzheimer's disease. They report that cellular prion proteins trigger the process by which amyloid-beta peptides block brain ... > full story -
Mouse Model Of Prion Disease Mimics Diverse Symptoms Of Human Disorder
November 28, 2008 — A comprehensive mouse model of inherited prion disease exhibits cognitive, motor and neurophysiological deficits that bear a striking resemblance to the symptoms experienced by patients with the ... > full story -
Protective Pathway In Stressed Cells Not So Helpful When It Comes To Prions
September 17, 2008 — Scientists have discovered that an important cellular quality control mechanism may actually be toxic to some brain cells during prion infection. The research proposes a new general mechanism of ... > full story -
Variant Of Mad Cow Disease May Be Transmitted By Blood Transfusions, According To Animal Study
August 29, 2008 — Blood transfusions are a valuable treatment mechanism in modern medicine, but can come with the risk of donor disease transmission. Researchers are continually studying the biology of blood products ... > full story -
First Atomic-level Look At A Protein That Causes Brain Disease
April 24, 2008 — For the first time, researchers have peered deeply at the atomic level into the protein that causes hereditary cerebral amyloid angiopathy -- a disease thought to cause stroke and dementia. The study ... > full story -
Prions Link Cholesterol To Neurodegeneration
February 12, 2008 — Prion infection of neurons increases the free cholesterol content in cell membranes. A new study suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause ... > full story
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