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No longer junk: Role of long noncoding RNAs in autism risk

Date:
March 24, 2014
Source:
Spectrum
Summary:
RNA acts as the intermediary between genes and proteins, but the function of pieces of RNA that do not code for protein has, historically, been less clear. Noncoding RNAs are emerging as important regulators of diverse cellular processes with implications for numerous human disorders.
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RNA acts as the intermediary between genes and proteins, but the function of pieces of RNA that do not code for protein has, historically, been less clear. Researchers have ignored these noncoding RNAs until recently for not complying with the central dogma of biology -- that a straight line runs from gene to RNA (transcription) to protein (translation). However, noncoding RNAs are emerging as important regulators of diverse cellular processes with implications for numerous human disorders.

Extensive research has already examined the function of microRNAs, a category of small evolutionarily conserved noncoding RNAs about 22 to 24 nucleotides in length that target protein-coding genes in a sequence-specific manner. A plethora of microRNAs are important for brain function and neuropsychiatric diseases, including autism.

Read the full article here: https://spectrumnews.org/opinion/viewpoint/no-longer-junk-role-of-long-noncoding-rnas-in-autism-risk/


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Materials provided by Spectrum. Note: Content may be edited for style and length.


Cite This Page:

Spectrum. "No longer junk: Role of long noncoding RNAs in autism risk." ScienceDaily. ScienceDaily, 24 March 2014. <www.sciencedaily.com/releases/2014/03/140324133117.htm>.
Spectrum. (2014, March 24). No longer junk: Role of long noncoding RNAs in autism risk. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2014/03/140324133117.htm
Spectrum. "No longer junk: Role of long noncoding RNAs in autism risk." ScienceDaily. www.sciencedaily.com/releases/2014/03/140324133117.htm (accessed May 23, 2017).

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