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Vitamin D deficiency may raise risk of getting COVID-19, study finds

Date:
September 3, 2020
Source:
University of Chicago Medical Center
Summary:
In a retrospective study of patients tested for COVID-19, researchers found an association between vitamin D deficiency and the likelihood of becoming infected with the coronavirus.
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In a retrospective study of patients tested for COVID-19, researchers at the University of Chicago Medicine found an association between vitamin D deficiency and the likelihood of becoming infected with the coronavirus.

"Vitamin D is important to the function of the immune system and vitamin D supplements have previously been shown to lower the risk of viral respiratory tract infections," said David Meltzer, MD, PhD, Chief of Hospital Medicine at UChicago Medicine and lead author of the study. "Our statistical analysis suggests this may be true for the COVID-19 infection."

The research team looked at 489 UChicago Medicine patients whose vitamin D level was measured within a year before being tested for COVID-19. Patients who had vitamin D deficiency (< 20ng/ml) that was not treated were almost twice as likely to test positive for the COVID-19 coronavirus compared to patients who had sufficient levels of the vitamin.

The study, "Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results," was published Sept. 3 in JAMA Network Open. Findings were previously reported on medRxiv, a preprint server for the health sciences.

Half of Americans are deficient in Vitamin D, with much higher rates seen in African Americans, Hispanics and individuals living in areas like Chicago where it is difficult to get enough sun exposure in winter.

"Understanding whether treating Vitamin D deficiency changes COVID-19 risk could be of great importance locally, nationally and globally," Meltzer said. "Vitamin D is inexpensive, generally very safe to take, and can be widely scaled."

Meltzer and his team emphasize the importance of experimental studies to determine whether vitamin D supplementation can reduce the risk, and potentially severity, of COVID-19. They also highlight the need for studies of what strategies for vitamin D supplementation may be most appropriate in specific populations. They have initiated several clinical trials at UChicago Medicine and with partners locally.


Story Source:

Materials provided by University of Chicago Medical Center. Original written by Gretchen Rubin. Note: Content may be edited for style and length.


Journal Reference:

  1. David O. Meltzer, Thomas J. Best, Hui Zhang, Tamara Vokes, Vineet Arora, Julian Solway. Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results. JAMA Network Open, 2020; 3 (9): e2019722 DOI: 10.1001/jamanetworkopen.2020.19722

Cite This Page:

University of Chicago Medical Center. "Vitamin D deficiency may raise risk of getting COVID-19, study finds." ScienceDaily. ScienceDaily, 3 September 2020. <www.sciencedaily.com/releases/2020/09/200903133007.htm>.
University of Chicago Medical Center. (2020, September 3). Vitamin D deficiency may raise risk of getting COVID-19, study finds. ScienceDaily. Retrieved May 20, 2024 from www.sciencedaily.com/releases/2020/09/200903133007.htm
University of Chicago Medical Center. "Vitamin D deficiency may raise risk of getting COVID-19, study finds." ScienceDaily. www.sciencedaily.com/releases/2020/09/200903133007.htm (accessed May 20, 2024).

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