Apr. 18, 2022 Researchers have found that heterozygous loss of the methyl-CpG binding protein Zbtb38 downregulated the expression of the transcription factors Nanog and Sox2, as well as genes involved in epiblast ...
Apr. 5, 2022 Researchers have revealed how an 'accordion effect' is critical to switching off genes, in a study that transforms the fundamentals of what we know about gene silencing. The finding expands ...
Apr. 1, 2022 How is the activity of genes regulated by the packaging of DNA? To answer this question, researchers developed a technique to measure both gene expression and DNA packaging at the same ...
Mar. 10, 2022 Animals often use highly specific signals to warn their herd about approaching predators. Surprisingly, similar behaviors are also observed among plants. Shedding more light on this phenomenon, ...
Feb. 28, 2022 A multidisciplinary team has devised a new approach to 3D imaging that captures DNA methylation, a key epigenetic change associated with learning in the brain. The scientists say their ...
Feb. 28, 2022 In humans and other eukaryotes, two principal epigenetic marks are known. A team has discovered a third, novel epigenetic mark -- one formerly known only in bacteria -- in bdelloid rotifers, small ...
Feb. 10, 2022 A new study has shown that the effects of pollutants can be transmitted over many generations in water fleas and may persist long enough to influence the evolutionary process. The research adds new ...
Feb. 8, 2022 Researchers discover a 'switch' specific to transcription factors that induce the genes essential for blood vessel development in postnatal periods. Mouse models further showed that the ...
Jan. 12, 2022 Hereditary diseases as well as cancers and cardiovascular diseases may be associated with a phenomenon known as genomic imprinting, in which only the maternally or paternally inherited gene is ...
Jan. 11, 2022 A team has shown that the CLASSY gene family regulates which parts of the genome are turned off in a tissue-specific manner. The work identifies the CLSY genes as major factors underlying epigenetic ...
Jan. 4, 2022 Researchers generated mice with a specific DNA sequence inverted to determine if orientation affects expression of a gene called H19. Expression can also be impacted if the surrounding DNA is altered ...
July 9, 2021 A new study provides a potential tool for unraveling the mystery of how experiences can cause inheritable changes to an animal's biology. By mating nematode worms, they produced permanent ...
July 1, 2021 Hereditary information is passed from parent to offspring in the genetic code, DNA, and epigenetically through chemically induced modifications around the DNA. New research has uncovered a mechanism ...
June 28, 2021 Researchers noted a significant difference in mice from mothers that were fed a diet rich in canola oil, compared with mothers fed a diet rich in corn oil. A maternal Omega 3-rich diet affected ...
June 21, 2021 Biologists have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics - an area of science ...
June 7, 2021 Computer simulations visualize in atomic detail how DNA opens while wrapped around ...
May 20, 2021 Small chemical 'epigenetic' modifications help plants control their genes. Baby plants erase these modifications to start with a fresh genome every generation. Scientists discovered a gene ...
May 13, 2021 B cells are the immune cells responsible for creating antibodies, and most produce antibodies in response to a pathogen or a vaccine. A small subset of B cells instead spontaneously make antibodies ...
May 6, 2021 The cerebellum -- a part of the brain once recognized mainly for its role in coordinating movement -- underwent evolutionary changes that may have contributed to human culture, language and tool use, ...
Apr. 16, 2021 Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch ...