Alzheimer's News

April 30, 2025

Top Headlines

New Body-Fluid Biomarker for Parkinson's Disease Discovered

Apr. 25, 2025 — Researchers have discovered a new biomarker for Parkinson's disease. A misfolded protein facilitates reliable diagnosis even in the early stages of Parkinson's disease in body ...

AI Helps Unravel a Cause of Alzheimer's Disease and Identify a Therapeutic Candidate

Apr. 25, 2025 — A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that ...

In Down Syndrome Mice, 40Hz Light and Sound Improve Cognition, Neurogenesis, Connectivity

Apr. 25, 2025 — A new study provides new evidence that sensory stimulation of a gamma-frequency brain rhythm may promote broad-based restorative neurological health ...

Immune Cells Drive Congenital Paralysis Disease

Apr. 25, 2025 — Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the brain appears to play a major role by over-activating ...

Latest Headlines

updated 1:45pm EDT

Even Light Exercise Could Help Slow Cognitive Decline in People at Risk of Alzheimer's

Apr. 24, 2025 — In a landmark clinical trial people at risk for Alzheimer's who exercised at low or moderate-high intensity showed less cognitive decline when ...

Exercise Boosts Brain Health -- Even When Energy Is Low

Apr. 24, 2025 — We know exercise is good for our body, but what about our brains? A new study suggests that exercise plays a crucial role in keeping our minds sharp, even when one of the brain's key energy sources ...

ATP Prevents Harmful Aggregation of Proteins Associated With Parkinson's and ALS

Apr. 23, 2025 — While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding their fundamental ...

Clinical Trials to Test Vaccine Against Alzheimer's-Promoting Tau Protein

Apr. 23, 2025 — Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

Metabolic Syndrome Linked to Increased Risk of Young-Onset Dementia

Apr. 23, 2025 — Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a new study. ...

Empathy Might Be Retained in Alzheimer's Disease

Apr. 23, 2025 — People with Alzheimer's disease may retain their ability to empathize, despite declines in other social abilities, finds a new ...

New Research Lays Groundwork for Early Detection of Alzheimer's Disease

Apr. 21, 2025 — A new study suggests that risk factors and biomarkers related to Alzheimer's disease are associated with cognition much earlier in life than previously recognized. The study highlights significant ...

Engineered Microglia Show Promise for Treating Alzheimer's and Other Brain Diseases

Apr. 21, 2025 — A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological ...

Integrative Approach Reveals Promising Candidates for Alzheimer's Disease Risk Factors or Targets for Therapeutic Intervention

Apr. 18, 2025 — A new study provides solutions to the pressing need to identify factors that influence Alzheimer's disease (AD) risk or resistance while providing an ...

Menopause at an Early Age Can Exacerbate Cognitive Decline

Apr. 16, 2025 — Why does dementia affect more women than men? To help solve this mystery, researchers uncovered a new risk factor: age of menopause ...

How Do Age, Sex, Hormones and Genetics Affect Dementia Biomarkers in the Blood?

Apr. 16, 2025 — A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood, according to a new ...

Towards Gene-Targeting Drugs Capable of Targeting Brain Diseases

Apr. 16, 2025 — Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex ...

Hereditary Alzheimer's: Blood Marker for Defective Neuronal Connections Rises Early

Apr. 16, 2025 — Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia ...

Apr. 16, 2025 — Drugs like Ozempic, other blood sugar-reducing medications, may stave off ...

Researchers May Have Solved Decades-Old Mystery Behind Benzodiazepine Side Effects

Apr. 14, 2025 — Identifying a key protein's role could improve the common mental health medications and point to new treatments for inflammation-related diseases, a medicinal chemist ...

Scientists Identify Key Enzyme in Alzheimer's Disease That Links Brain Inflammation to Memory Loss

Apr. 14, 2025 — A research team has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD). The study provides critical insights into how ...

New Key Genes in Parkinson's Disease Identified Using CRISPR Technology

Apr. 11, 2025 — A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who ...

Eight or More Drinks Per Week Linked to Signs of Injury in the Brain

Apr. 9, 2025 — Heavy drinkers who have eight or more alcoholic drinks per week have an increased risk of brain lesions called hyaline arteriolosclerosis, signs of brain injury that are associated with memory and ...

Father With Alzheimer's? You May Be More at Risk of Brain Changes

Apr. 9, 2025 — While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be ...

New Insights Into Neurodegeneration Using Human 'Mini Brains'

Apr. 9, 2025 — Researchers have discovered a new way that neurons act in neurodegeneration by using human neural organoids -- also known as 'mini-brain' models -- from patients with frontotemporal lobar ...

More Opportunities to Test for Alzheimer's Using New Analytical Method

Apr. 9, 2025 — A simpler method of analyzing blood samples for Alzheimer's disease has been tested in a large multi-center ...

Long-Term Effects of Obesity on Brain and Cognitive Health

Apr. 9, 2025 — With the global prevalence of obesity on the rise, it is crucial to explore the neural mechanisms linked to obesity and its influence on brain and cognitive health. However, the impact of obesity on ...

Potential Alzheimer's Disease Therapeutic Target Identified in Brain Immune Cells

Apr. 9, 2025 — Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer's disease (AD), but its role in the brain was unknown until now. Researchers ...

Novel Drug Delivery Platform Paves Way to Potential New Treatments for Alzheimer's, Other Brain-Related Disorders

Apr. 9, 2025 — Researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's ...

Discovery of Mitochondrial Protein Opens Path to Therapeutic Advances for Heart and Alzheimer's Disease

Apr. 8, 2025 — Calcium transport into and out of mitochondria -- the powerhouses of cells -- is central to cellular energy production and cell death. To maintain the balance of calcium within these powerhouses, ...

Researchers Discover Natural Compound May Slow ALS and Dementia

Apr. 8, 2025 — A new study shows a compound found in certain fruits and vegetables could hold key to treating neurodegenerative ...

ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study

Apr. 8, 2025 — Experimental drug NU-9 -- a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves ...

Eye Health Linked to Dementia Risk

Apr. 8, 2025 — Researchers discovered the blood vessels at the back of the eye -- called retinal microvasculature -- can show early signs someone is at risk of developing ...

Key Differences Between Visual And Memory-Led Alzheimer's Discovered

Apr. 2, 2025 — Differences in the distribution of certain proteins and markers in the brain may explain why some people first experience vision changes instead of memory loss in Alzheimer's disease, finds a ...

Blood Test May Rule out Future Dementia Risk

Apr. 2, 2025 — Researchers have demonstrated how specific biomarkers in the blood can predict the development of dementia up to ten years before diagnosis, among older adults living independently in the ...