Disorders and Syndromes News

November 25, 2025

Top Headlines

The Body Trait That Helps Keep Your Brain Young

Nov. 25, 2025 Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective ...

Scientists Find a Hidden Weak Spot That May Trigger Alzheimer’s

Nov. 25, 2025 Scientists have found that a mutation tied to Alzheimer’s disrupts the production and quality of exosomes—tiny cell-made communication packets. Cells with the defective SORLA protein generate fewer exosomes and ones far less able to support ...

Your Brain Shows Damage Before Your Blood Pressure Even Rises

Nov. 24, 2025 Hypertension begins harming the brain surprisingly early, even before measurable blood pressure increases. Key cells related to blood vessels, signaling, and myelin maintenance begin aging prematurely and malfunctioning. These disruptions resemble ...

A Tiny Enzyme May Hold the Key to Safer Pain Relief

Nov. 23, 2025 Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or sensation. This enzyme, called VLK, modifies ...

Boosting One Protein Helps the Brain Protect Itself from Alzheimer’s

Nov. 23, 2025 Researchers discovered that raising the protein Sox9 can help the brain’s astrocytes clear out toxic plaque buildup linked to Alzheimer’s. In mouse models that already showed memory problems, activating these cells improved cognitive ...

Hidden Microglia Switch Helps Protect the Brain from Alzheimer’s

Nov. 22, 2025 Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an outsized ability to keep the brain healthier. When ...

New Nasal Nanodrops Wipe Out Brain Tumors in Mice

Nov. 22, 2025 A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach the brain without invasive surgery. When paired ...

Scientists Reveal a Hidden Hormone Switch for Learning

Nov. 21, 2025 Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain ...

Simple Amino Acid Supplement Greatly Reduces Alzheimer’s Damage

Nov. 21, 2025 Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered plaque levels, reduced inflammation, and improved ...

How to Keep Ozempic/Wegovy Weight Loss Without the Nausea

Nov. 18, 2025 Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments that keep the benefits of weight loss while reducing ...

A Surprising CBD Advance Calms Pain Without Side Effects

Nov. 18, 2025 Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or memory side effects. Surprisingly, the pain relief ...

Daily Music Listening Linked to Big Drop in Dementia Risk

Nov. 17, 2025 Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in ...

Latest Headlines

updated 1:02pm EST

Simple Molecule Shows Remarkable Alzheimer’s Reversal in Rats

Nov. 19, 2025 Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also ...

Supercomputer Creates the Most Realistic Virtual Brain Ever

Nov. 18, 2025 Researchers have created one of the most detailed virtual mouse cortex simulations ever achieved by combining massive biological datasets with the extraordinary power of Japan’s Fugaku ...

Smoking Cannabis With Tobacco May Disrupt the Brain’s “bliss Molecule”

Nov. 15, 2025 Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed ...

Scientists Melt Early Protein Clumps and Shut Down Alzheimer’s Damage

Nov. 15, 2025 Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril ...

Your Anxiety May Be Controlled by Hidden Immune Cells in the Brain

Nov. 13, 2025 Researchers have uncovered surprising evidence that anxiety may be controlled not by neurons but by two dueling groups of immune cells inside the brain. These microglia act like biological ...

What Brain Scans Reveal About Soccer Fans’ Passion and Rage

Nov. 11, 2025 Researchers scanning soccer fans’ brains found that wins trigger bursts of reward activity while losses dampen control signals. The results show how loyalty and rivalry can override logic, turning ...

Clearing Brain Plaques Isn’t Enough to Heal Alzheimer’s

Nov. 11, 2025 Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and ...

Scientists Find Brain Chemical Tied to Trauma and Depression

Nov. 10, 2025 Researchers identified SGK1 as a key chemical connecting childhood trauma to depression and suicidal behavior. High SGK1 levels were found in the brains of suicide victims and in people with genetic ...

A Simple DNA Test Could Reveal the Right Antidepressant for You

Nov. 9, 2025 Millions struggle with depression and anxiety, often enduring long waits for effective treatment. Scientists in Sweden, Denmark, and Germany are developing a genetic test to predict which medications ...

Common Antidepressant Found to Work in Just Two Weeks

Nov. 8, 2025 Sertraline (Zoloft) may relieve emotional symptoms of depression and anxiety within two weeks, while physical side effects stabilize later. The research highlights how antidepressants can act on ...

Scientists Find Brain Cells That Could Stop Alzheimer’s

Nov. 8, 2025 Researchers have identified special immune cells in the brain that help slow Alzheimer’s. These microglia work to reduce inflammation and block the spread of harmful proteins. They appear to ...

Mini Llama Proteins Show Promise for Alzheimer’s Treatment

Nov. 6, 2025 Miniature antibodies from camels and llamas can slip into the brain more easily than conventional drugs, offering a new way to treat disorders like Alzheimer’s and schizophrenia. Researchers say ...

Common Acne Drug May Protect Against Schizophrenia

Nov. 6, 2025 Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the ...

Scientists Find Hidden Brain Source That Fuels Dementia

Nov. 6, 2025 Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and ...

Walking May Be the Brain’s Best Defense Against Alzheimer’s

Nov. 4, 2025 Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of ...

A Groundbreaking Brain Map Could Revolutionize Parkinson’s Treatment

Nov. 3, 2025 Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides ...

A Breakthrough Map Reveals How the Brain Really Works

Nov. 5, 2025 Scientists have shown that brain connectivity patterns can predict mental functions across the entire brain. Each region has a unique “connectivity fingerprint” tied to its role in cognition, ...

Scientists May Have Found How to Reverse Memory Loss in Aging Brains

Nov. 5, 2025 Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older ...

Alzheimer’s Might Be Powered by a Broken Sleep-Wake Cycle

Nov. 3, 2025 Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are ...

Gum Disease May Quietly Damage the Brain, Scientists Warn

Oct. 29, 2025 People with gum disease may have higher levels of brain white matter damage, a new study finds. Researchers observed that participants with gum disease had significantly more white matter ...

Running Fixes What Junk Food Breaks in the Brain

Oct. 21, 2025 New research reveals that exercise counteracts the mood-damaging effects of a Western-style diet through specific gut and hormonal mechanisms. Running restored metabolites tied to mental well-being ...

Brain Fog During Menopause? Here’s What’s Really Going on

Oct. 21, 2025 Menopause brings profound shifts not just in hormones but in the very structure of the brain. Scientists have found that gray matter in regions tied to memory and thinking can shrink, while white ...

Scientists Detect Hidden Brain Damage Years Before MS Symptoms

Oct. 21, 2025 Scientists at UCSF have uncovered evidence that multiple sclerosis silently damages the brain years before diagnosis. By studying proteins in blood samples, they identified early immune signals and ...

Your ZIP Code Could Reveal Your Risk of Dementia

Oct. 31, 2025 People living in socially and economically disadvantaged neighborhoods may face higher dementia risks, according to new research from Wake Forest University. Scientists found biological signs of ...

From Poison to Power: How Lead Exposure Helped Shape Human Intelligence

Oct. 16, 2025 Long before humans built cities or wrote words, our ancestors may have faced a hidden threat that shaped who we became. Scientists studying ancient teeth found that early humans, great apes, and even ...

Online Brain Training Reverses 10 Years of Aging in Memory and Learning

Oct. 29, 2025 A new McGill-led study reveals that digital brain exercises can rejuvenate aging brain systems responsible for learning and memory. Older adults using BrainHQ for 10 weeks showed restored cholinergic ...

Tiny Brain Nanotubes Found by Johns Hopkins May Spread Alzheimer’s

Oct. 16, 2025 Johns Hopkins scientists uncovered microscopic “nanotube” channels that neurons use to transfer toxic molecules. While this process clears waste, it can also spread harmful proteins like ...

Your Brain’s Power Supply May Hold the Key to Mental Illness

Oct. 14, 2025 Groundbreaking Harvard research is exposing hidden energy failures inside brain cells that may drive major psychiatric conditions. By studying reprogrammed neurons, scientists are revealing how ...

Your DNA May Shape How You Use Cannabis

Oct. 20, 2025 A major collaboration between UC San Diego and 23andMe identified genes that shape cannabis use behaviors. The study linked the CADM2 and GRM3 genes to cannabis use and connected these patterns to ...

Your Skin Could Warn of Hidden Mental Health Trouble

Oct. 13, 2025 People experiencing their first psychotic episode who also have skin conditions such as rashes or itching are at greater risk of depression and suicidal thoughts, according to new research presented ...