CRISPR Gene Editing News

April 30, 2025

Top Headlines

No More Copy-Pasting: DNA Base Editing for Better Lactobacillus Strains

Apr. 24, 2025 — A team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms. This technique is indistinguishable from natural variation and enabled the researchers to create a strain that doesn't produce ...

Researchers Use Machine Learning to Engineer 'Bespoke Enzymes' for Gene Editing

Apr. 22, 2025 — Genome editing has advanced at a rapid pace with promising results for treating genetic conditions -- but there is always room for improvement. A new paper showcases the power of scalable protein ...

New Tool for Cutting DNA: Promising Prospects for Biotechnology

Apr. 14, 2025 — A team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a derivative of the immune ...

How Bacteria 'Vaccinate' Themselves With Genetic Material from Dormant Viruses

Mar. 21, 2025 — Scientists say they have shed new light on how bacteria protect themselves from certain phage invaders -- by seizing genetic material from weakened, dormant phages and using it to 'vaccinate' ...

Latest Headlines

updated 4:19pm EDT

New CRISPR Tool Enables More Seamless Gene Editing -- And Improved Disease Modeling

Mar. 20, 2025 — Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific ...

New CRISPRs Expand Upon the Original's Abilities

Mar. 13, 2025 — Researchers have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox. Of the new recruits, one ...

Researchers Develop Enhanced Method for Wastewater Surveillance of Antibiotic Resistance

Mar. 3, 2025 — Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals. To better ...

Bacterial 'Jumping Genes' Can Target and Control Chromosome Ends

Mar. 6, 2025 — Transposons, or 'jumping genes' -- DNA segments that can move from one part of the genome to another -- are key to bacterial evolution and the development of antibiotic resistance. Researchers have ...

Breakthrough CRISPR-Based Test Offers Faster, More Accurate Diagnosis for Fungal Pneumonia

Mar. 3, 2025 — Pneumocystis jirovecii pneumonia (PJP) is the most common fungal pneumonia in children. But current diagnostic methods can take days an require an ...

How Mitochondria Drive Autophagy

Feb. 13, 2025 — A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...

Activating the Hidden Pharmaceutical Potential of Bacteria

Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be used as active ingredients to treat diseases such as infections or cancer. The blueprints for these molecules can be found in the ...

CRISPR-Cas Technology: Balancing Efficiency and Safety

Dec. 4, 2024 — Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the ...

New Gene Drive Reverses Insecticide Resistance in Pests... Then Disappears

Nov. 22, 2024 — Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e-Drive' that reverses ...

Labeling Cell Particles With Barcodes

Nov. 19, 2024 — Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. ...

Using CRISPR to Decipher Whether Gene Variants Lead to Cancer

Nov. 12, 2024 — Researchers have combined two gene editing methods. This enables them to quickly investigate the significance of many genetic mutations involved in the development and treatment of ...

Finding Function for Noncoding RNAs Using a New Kind of CRISPR

Nov. 7, 2024 — Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

Use of 'Genetic Scissors' Carries Risks

Nov. 6, 2024 — The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease. However, researchers have now shown that there is a risk of inadvertently ...

Researchers Discover Underlying Mechanisms That Make CRISPR an Effective Gene Editing Tool

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical findings could lead ...

Structure of a Eukaryotic CRISPR-Cas Homolog, Fanzor2, Shows Its Promise for Gene Editing

Oct. 1, 2024 — Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering ...

Compact 'Gene Scissor' Enables Effective Genome Editing

Sep. 23, 2024 — CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known 'gene scissor' but is much smaller and ...

CREME AI and CRISPR in Tandem

Sep. 16, 2024 — CREME is a virtual laboratory that allows scientists to simulate specific decreases in gene activity. It offers a powerful new tool for identifying and understanding important parts of the genome. ...

CRISPR/Cas9 Modifies Euglena to Create Potential Biofuel Source

Sep. 13, 2024 — Through genome editing using CRISPR/Cas9, researchers stably create euglena mutants that can produce wax esters with improved cold flow, making the esters suitable as feedstock for ...

Beyond Needles: Introducing a New, Nature-Based Approach for Delivering Cargo Into Egg Cells

Sep. 11, 2024 — A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed, resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many ...

Genomic Dark Matter Solves Butterfly Evolutionary Riddle

Aug. 30, 2024 — Researchers have uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. The team discovered that an RNA molecule, rather than a protein as ...

Immune System That Bacteria Use to Respond to Viral Infections

Aug. 26, 2024 — An article highlights new insights into the PARIS, an immune system that bacteria use to respond to viral ...

Bacteria Encode Hidden Genes Outside Their Genome--Do We?

Aug. 9, 2024 — A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic ...

Precise Genetics: New CRISPR Method Enables Efficient DNA Modification

July 30, 2024 — A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. ...

A New Addition to the CRISPR Toolbox: Teaching the Gene Scissors to Detect RNA

July 16, 2024 — CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel ...

Big Gain in Battle Against Harmful Bacteria

July 10, 2024 — An unexpected find has enabled important progress to be made in the battle against harmful ...

New Tool Enables Faster, More Cost-Effective Genome Editing of Traits to Improve Agriculture Sustainability

June 26, 2024 — New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture ...

Modifying Genomes of Tardigrades to Unravel Their Secrets

June 13, 2024 — Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. ...

Scientists Engineer Yellow-Seeded Camelina With High Oil Output

June 11, 2024 — Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates ...

Fine-Tuning Leaf Angle With CRISPR Improves Sugarcane Yield

June 10, 2024 — A CABBI research team has used CRISPR/Cas9 gene editing to optimize leaf angle in sugarcane, increasing the amount of sunlight it captures and the amount of biomass it ...

Changes Upstream: RIPE Team Uses CRISPR/Cas9 to Alter Photosynthesis for the First Time

June 7, 2024 — Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, ...