Huntington's Disease News

October 23, 2026

Top Headlines

Brain Cells Meant to Protect Us May Be Fueling Cognitive Decline

Oct. 17, 2026 Scientists have uncovered a surprising cause of age-related cognitive decline involving brain cells previously thought to be entirely beneficial. As these cells become dysfunctional, they can produce abnormal amounts of myelin, disrupting nerve ...

Scientists Uncover a Hidden Map of the Brain with 539 Distinct Regions

Oct. 13, 2026 Scientists have uncovered a hidden layer of organization in the brain by creating the first detailed 3D map of its lipids, the fatty molecules essential for brain structure and communication. By analyzing millions of measurements from mouse brains, ...

After 30 Years, Scientists Finally Have a Drug for a Deadly Brain Disease

Oct. 12, 2026 The FDA has approved the first drug that directly targets Alexander disease, a devastating neurological disorder affecting fewer than one in a million people. Developed through decades of research, Zanvastro showed promising results in clinical ...

Alzheimer’s Risk Gene APOE4 May Have a Reversible Weakness

Oct. 1, 2026 The Alzheimer’s risk gene APOE4 may actively damage brain blood vessels and sabotage the cellular systems that remove harmful proteins. Researchers were able to reverse some of these effects in experiments, revealing promising new targets for ...

Stanford Scientists Discover a Seafood That Can Reverse Signs of Aging

Sep. 4, 2026 A substance found in edible sea squirts appeared to reverse several signs of aging in older mice. Plasmalogen supplements improved memory and learning, strengthened connections between brain cells, reduced inflammation, and even helped the mice grow ...

One Immune Switch May Help Drive Aging Across the Body

Sep. 3, 2026 Aging may be partly fueled by immune cells losing their ability to clear away damaged, inflammation-promoting cells. Blocking a single receptor restored that cleanup process in mice, reducing inflammation and helping their organs, muscles, and ...

AI-designed “Intrabodies” Could Unlock New Treatments for Alzheimer’s, Parkinson’s and MND

Aug. 19, 2026 Researchers have developed a new way to turn ordinary antibodies into tiny disease-fighting molecules that can work inside human cells, potentially opening new paths for treating Alzheimer’s, ...

A Stress Hormone May Help the Brain Repair Itself

Aug. 14, 2026 A surprising stress-related signal may help the brain repair itself after injury. Researchers found that myelin-producing precursor cells rapidly release the stress hormone CRH near damaged brain tissue, helping control how those cells mature and ...

Scientists May Have Found Aging’s Hidden Trigger for Brain Disease

Aug. 3, 2026 Scientists have identified a molecular switch that may help explain why aging makes the brain more vulnerable to diseases such as ALS and Huntington’s. In worms, the protein EPS8 builds up with age and triggers signaling that encourages toxic ...

Scientists Discover a Protein That Protects the Brain from Alzheimer’s Damage

July 20, 2026 A protein called SORLA may act as a powerful defense against the toxic tau tangles involved in Alzheimer’s disease. Mice with extra SORLA had less tau accumulation, less brain atrophy, and ...

A Surprising Brain Discovery Is Forcing Scientists to Rethink Movement Disorders

July 1, 2026 A surprising discovery is overturning a long-held assumption about how the brain’s movement center works. Researchers found that two key cerebellar cell types—thought to be tightly linked—often ...

A Hidden Gene Finally Explains This Rare Neurological Disorder

June 13, 2026 Scientists have uncovered a surprising new genetic cause of a rare movement disorder after analyzing nearly 3,000 patients with conditions affecting coordination and muscle control. The team identified mutations in a gene called CD99L2, previously ...

Latest Headlines

updated 8:09am EDT

Protein Traffic Jams May Explain Aging, Memory Loss, and Alzheimer’s

May 29, 2026 Scientists at Stanford may have uncovered a hidden reason our brains decline with age. Studying the ultra-short-lived turquoise killifish, researchers discovered that the cellular machinery ...

May 27, 2026 A drug combo widely explored for anti-aging may actually damage the brain, according to new mouse research showing severe loss of myelin and changes linked to “chemo brain.” Surprisingly, the ...

Scientists Create Supercharged Vitamin K That Helps the Brain Heal Itself

May 27, 2026 Scientists in Japan have created powerful new vitamin K-based compounds that may help the brain regenerate lost neurons — a breakthrough that could one day change how diseases like Alzheimer’s ...

Scientists Reversed Memory Loss by Recharging the Brain’s Tiny Engines

May 16, 2026 Researchers have shown for the first time that malfunctioning mitochondria — the cell’s energy generators — may directly cause cognitive decline in neurodegenerative diseases. By creating a new ...

This “rotten Egg” Brain Gas Could Be the Key to Fighting Alzheimer’s Disease

Apr. 8, 2026 Scientists have uncovered a surprising new player in Alzheimer’s disease: a protein called CSE that helps produce tiny amounts of hydrogen sulfide ...

Scientists Turn Brain Cells Into Alzheimer’s Plaque Cleaners

Mar. 11, 2026 Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody ...

Scientists Find ‘master Regulator’ That Could Reverse Brain Aging

Jan. 18, 2026 Researchers have identified OTULIN, an immune-regulating enzyme, as a key trigger of tau buildup in the brain. When OTULIN was disabled, tau vanished from neurons and brain cells remained healthy. ...

Why Multiple Sclerosis Slowly Steals Balance and Movement

Jan. 6, 2026 Many people with multiple sclerosis struggle with balance and coordination, and this study uncovers a hidden reason why. Researchers found that inflammation in the brain disrupts the energy supply of ...

A New Drug Could Stop Alzheimer’s Before Memory Loss Begins

Dec. 22, 2025 New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early ...

Your Body May Already Have a Molecule That Helps Fight Alzheimer’s

Nov. 27, 2025 Spermine, a small but powerful molecule in the body, helps neutralize harmful protein accumulations linked to Alzheimer’s and Parkinson’s. It encourages these misfolded proteins to gather into ...

Common Acne Drug May Protect Against Schizophrenia

Nov. 6, 2025 Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the ...

Scientists Detect Hidden Brain Damage Years Before MS Symptoms

Oct. 21, 2025 Scientists at UCSF have uncovered evidence that multiple sclerosis silently damages the brain years before diagnosis. By studying proteins in blood samples, they identified early immune signals and ...

Breakthrough Compounds May Reverse Nerve Damage Caused by Multiple Sclerosis

Oct. 11, 2025 Researchers have identified two compounds, K102 and K110, that could repair the nerve damage from multiple sclerosis. These drugs help regenerate the protective myelin sheath and balance immune ...

Supercharged Vitamin K Could Help the Brain Heal Itself

Oct. 14, 2025 Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The new compounds, which combine vitamin K with retinoic acid, activate the ...

Hidden Brain Signal Reveals Alzheimer’s Years Before Symptoms

Sep. 22, 2025 A new study has revealed that TSPO, a protein linked to brain inflammation, rises long before Alzheimer’s symptoms appear. Researchers tracked the protein in genetically engineered mice and ...

Scientists Reversed Memory Loss by Powering the Brain’s Tiny Engines

Aug. 12, 2025 Scientists have discovered a direct cause-and-effect link between faulty mitochondria and the memory loss seen in neurodegenerative diseases. By creating a novel tool to boost mitochondrial activity ...

Gene Editing Disrupts Huntington's Mutation in Mice

May 28, 2025 Researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia. If longer than a certain threshold length, these sequences grow ...

Research Untangles Role of Stress Granules in Neurodegenerative Disease

May 28, 2025 Scientists found that stabilizing stress granules suppresses the effects of ALS-causing mutations, correcting previous models that imply stress granules promote amyloid ...

Sugar-Coated Nanotherapy Dramatically Improves Neuron Survival in Alzheimer's Model

May 14, 2025 In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The ...

Study Finds One Protein That Mitigates Huntington's Disease, and One That Exacerbates It

May 5, 2025 Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell ...

First Synthetic 'Mini Prion' Shows How Protein Misfolding Multiplies

Apr. 28, 2025 Prions transmit their abnormally folded shape onto other proteins. Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the ...

The Brain Resorts to Myelin When Other Brain Nutrients Are Depleted

Apr. 10, 2025 Marathon runners experience reversible changes in their brain myelin. These findings indicate that myelin (a substance that surrounds the neurons) exhibits behavior that was previously unknown, and ...

ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study

Apr. 8, 2025 Experimental drug NU-9 -- a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves ...

Brain's Own Repair Mechanism: New Neurons May Reverse Damage in Huntington's Disease

Apr. 7, 2025 New research shows that the adult brain can generate new neurons that integrate into key motor circuits, findings that may point to a new way to treat neurogenerative ...

New 4D Brain Map Reveals Potential Early Warning Signs of Multiple Sclerosis

Feb. 27, 2025 Using an animal model of multiple sclerosis (MS), researchers have created a four-dimensional brain map that reveals how lesions similar to those seen in human MS form. These findings provide a ...

Mystery Solved: New Study Reveals How DNA Repair Genes Play a Major Role in Huntington's Disease

Feb. 11, 2025 A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

New Drug Shows Promise in Restoring Vision for People With Nerve Damage

Jan. 24, 2025 Researchers have found a promising drug candidate that could help restore vision in individuals with multiple sclerosis (MS) and other neurological conditions that damage ...

Researchers Map the Brain's Self-Healing Abilities After Stroke

Jan. 24, 2025 A new study sheds light on one of the most severe consequences of stroke: damage to the brain's 'cables'-- the so-called nerve fibers -- which leads to permanent ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials

Jan. 17, 2025 Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's ...

Study Finds Surprising Way That Genetic Mutation Causes Huntington's Disease, Transforming Understanding of the Disorder

Jan. 16, 2025 Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the ...