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Birth Defects News

December 18, 2025

Top Headlines

 

More than 20% of young adults say they use cannabis or alcohol to fall asleep, with cannabis leading by a wide margin. Researchers warn this strategy can backfire, disrupting sleep quality and increasing the risk of long-term sleep and substance-use ...
A missing brain molecule may be disrupting neural wiring in Down syndrome, according to new research. Replacing it in adult mice rewired brain circuits and improved brain flexibility, challenging the ...
Researchers used miniature human brains grown in the lab to uncover why certain genetic mutations lead to abnormally small brains. Changes in actin disrupted the orientation of early brain cell divisions, causing crucial progenitor cells to ...
Cases of colorectal cancer in younger adults are climbing worldwide, driven by lifestyle changes and inherited genetic risks. Diet, obesity, and lack of early screening are playing a major role in this shift. New genetic tests offer hope for earlier ...
Researchers discovered that children who went back to school during COVID experienced far fewer mental health diagnoses than those who stayed remote. Anxiety, depression, and ADHD all declined as in-person learning resumed. Healthcare spending tied ...
Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes this protection, allowing harmful molecules to damage cell membranes and trigger early dementia. Mouse and cell studies showed ...
Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the earliest stages of embryonic development. These mosaic mutations often go undetected yet can still be passed on and cause ...
A major review across 73 countries finds that access to antiseizure medications is rising, but safe prescribing isn’t keeping pace. Valproate—linked to serious birth defects—remains widely used in many regions despite WHO warnings. Limited ...
The study reveals that widely used heart-attack risk calculators fail to flag nearly half of those who will soon experience a cardiac event. Even the newer PREVENT model misclassifies many patients as low-risk. Since most people develop symptoms ...
Scientists have found that a mutation tied to Alzheimer’s disrupts the production and quality of exosomes—tiny cell-made communication packets. Cells with the defective SORLA protein generate fewer exosomes and ones far less able to support ...
Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and interferon-responsive T cells create a self-sustaining ...
Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was ...

Latest Headlines

updated 10:49am EST

Earlier Headlines

 

Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the ...

Long-term melatonin use for sleep problems may come with unexpected heart dangers. Researchers found that chronic users were almost twice as likely to die and 3.5 times more likely to be hospitalized ...

Boston researchers linked nighttime light exposure to greater stress-related brain activity and inflamed arteries, signaling a higher risk of heart disease. The study suggests that artificial light ...

Most U.S. adults don’t realize alcohol raises cancer risk, and drinkers themselves are the least aware. Scientists say targeting these misbeliefs could significantly reduce alcohol-related cancer ...

A newly identified disorder, MINA syndrome, results from a mutation in the NAMPT protein that deprives motor neurons of energy, leading to severe movement problems. The discovery not only deepens ...

UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s ...

Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. Unlike ...

Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By ...

Semaglutide, tirzepatide, and other GLP-1 drugs appear to slow alcohol absorption and blunt its intoxicating effects, according to new research. The study found participants on these medications felt ...

Long before humans built cities or wrote words, our ancestors may have faced a hidden threat that shaped who we became. Scientists studying ancient teeth found that early humans, great apes, and even ...

Scientists have identified mutations in the CPD gene as a key cause of a rare congenital hearing loss, revealing how disruptions in arginine and nitric oxide signaling damage sensory cells in the ...

People experiencing their first psychotic episode who also have skin conditions such as rashes or itching are at greater risk of depression and suicidal thoughts, according to new research presented ...

Young rats given a ketogenic diet were largely protected from the mental and behavioral issues caused by prenatal stress. The high-fat, low-carb diet appeared to safeguard brain development and ...

Stanford scientists have solved a long-standing challenge in growing brain organoids by using a simple food additive to keep them from sticking together. The breakthrough enables the production of ...

EMBL researchers created SDR-seq, a next-generation tool that decodes both DNA and RNA from the same cell. It finally opens access to non-coding regions, where most disease-associated genetic ...

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid ...

Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing ...

Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

Men’s heavy drinking is fueling a hidden crisis affecting millions of women and children worldwide. The harms, from violence to financial instability, are especially severe where gender inequality ...

A new study shows glioblastoma isn’t confined to the brain—it erodes the skull and hijacks the immune system within skull marrow. The cancer opens channels that let inflammatory cells enter the ...

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