Colitis News

June 13, 2025

Top Headlines

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 — Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases ...

Mediterranean Diet Provides Symptom Relief for Patients With IBS in Pilot Study

May 30, 2025 — In a comparative pilot study, the Mediterranean diet and the low FODMAP diet both provided relief for patients with ...

IBD on the Rise: International Research Highlights Spread in Africa, Asia, and Latin America

May 28, 2025 — New research conducted by an international consortium shows that IBD and related conditions are now spreading through developing regions in Africa, Asia, and Latin ...

Oxygen Deprivation Promotes Colon Cancer Growth

May 21, 2025 — Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help sustain the inflammatory fibroblasts, which also ...

Colonic Inflammation Explains Missing Link Between Obesity and Beta-Cell Proliferation

May 9, 2025 — How does obesity affect insulin production? Researchers are shining light on new stages of the ERK ...

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 1, 2025 — A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study introduced a ...

Lower Screening Age Calls for More Tailored Bowel Cancer Surveillance

Apr. 30, 2025 — Australia's recent move to lower the starting age for bowel (colorectal) cancer screening from 50 down to 45 years old will mean better outcomes -- but it will also increase the burden on an already struggling healthcare system, warn researchers. ...

Cerebral Palsy Medications Given to Adults May Not Match Needs

Apr. 17, 2025 — Some medications are seen as a 'fix-all' solution, not addressing the root ...

Patient Navigators Improve Colonoscopy Rates After Abnormal Stool Tests, Study Shows

Mar. 31, 2025 — Timely follow-up colonoscopies can reduce the mortality rate from colorectal cancer, and patient navigators can play an important role in facilitating ...

'Switch' Allows Intestinal Cells to Regenerate After Injury

Mar. 25, 2025 — Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of molecular, cellular, and developmental biology have ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

Study Confirms Safety and Efficacy of Higher-Dose-Per-Day Radiation for Early-Stage Prostate Cancer

Mar. 18, 2025 — A large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without ...

Latest Headlines

updated 11:39am EDT

Treating Chronic Inflammatory Diseases With JAK Inhibitors

Mar. 17, 2025 — Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. Since ...

Gut Bacteria Heal the Colon

Mar. 10, 2025 — Scientists have uncovered how a gut bacterium, Clostridium scindens, aids in healing intestinal injuries by restoring bile acid balance. Their findings could pave the way for new treatments for ...

Focus on the Gut-Liver Axis: Semisynthetic Bile Acid Has Anti-Inflammatory Effects on the Gut

Mar. 13, 2025 — A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA ...

Possible Biomarker Identified for Crohn's Disease With Arthritis Type

Mar. 5, 2025 — People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential ...

School Absence Patterns Could ID Children With Chronic GI Disorders, Research Suggests

Mar. 4, 2025 — Children who frequently miss school because of abdominal complaints are far more likely to be suffering from chronic disorders such as irritable ...

Synthetic Microbiome Therapy Suppresses Bacterial Infection Without Antibiotics

Mar. 3, 2025 — A synthetic microbiome therapy, tested in mice, holds promise as a new treatment for C. difficile, a notoriously difficult-to-treat bacterial ...

Ginger Compound Has Potential to Treat Inflammatory Bowel Disease

Feb. 19, 2025 — Researchers have found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD). While researchers ...

Research Shows Blood Test May Provide Personalized Dietary Therapy for Patients With Irritable Bowel Syndrome

Feb. 13, 2025 — Study participants who went on an IgG-based elimination diet--based on a novel blood test--experienced less abdominal pain than those on a sham ...

Microbiome as a Potential Key to Better Treatment: Clinical Study on New Therapy for Crohn's Disease

Feb. 11, 2025 — A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six ...

Beyond the Gut: A New Frontier in IBS Treatment by Targeting the Brain

Feb. 5, 2025 — Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers have now discovered that opioid delta-receptor agonists ...

Study Establishes Link Between Early Side Effects from Prostate Cancer Radiation and Long-Term Side Effects

Jan. 31, 2025 — Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, ...

Could Fecal Microbiota Transplantation Help Patients Heal After Stem Cell Transplantation?

Jan. 28, 2025 — A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood ...

Blood Test Could Guide Use of Anti-Inflammatory Drug Celecoxib to Reduce Risk of Colon Cancer Recurrence

Jan. 28, 2025 — A data analysis from a randomized clinical trial for stage 3 colon cancer patients found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit ...

PET Probe Images Inflammation With High Sensitivity and Selectivity

Jan. 22, 2025 — Researchers have developed a breakthrough method to detect inflammation in the body using positron emission tomography (PET) imaging. This innovative probe targets CD45, a marker abundantly expressed ...

Inflammation May Explain Stomach Problems in Psoriasis Sufferers

Jan. 20, 2025 — People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research. These changes in ...

Wearable Devices Can Detect and Predict Inflammatory Bowel Disease Flare-Ups

Jan. 16, 2025 — Data collected by wearable technology can identify disease flare-ups up to seven weeks in ...

Fatal Neurodegenerative Disease in Kids Also Affects the Bowel

Jan. 15, 2025 — Researchers have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest study, a team showed that gene ...

Hidden Mechanism of Swallowing Revealed by Caenorhabditis Elegans

Dec. 20, 2024 — New researchers uncover the role of Piezo channels that sense pressure in the digestive tract and regulate swallowing behavior. The research opens new opportunities for developing treatments for ...

Potential Culprit Identified in Lingering Crohn's Disease Symptoms

Dec. 19, 2024 — A study may explain why some patients with Crohn's disease continue to experience symptoms, even in the absence of ...

How a New Gut Microbe Drives the Gut-Lung Axis

Dec. 19, 2024 — A team has discovered a new communication pathway between the gut and lung. Their findings highlight how a little-known member of the gut microbiome reshapes the lung immune environment to have both ...

Researchers Find Previously Unknown Links Between Microbial Bile Acids and the Risk of Colon Cancer

Dec. 16, 2024 — Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect ...

Ugh, My Stomach: Identifying Amino Acids That Prevent Sporulation in Food Poisoning

Dec. 12, 2024 — A team analyzed the amino acids that affect the formation of spores in a bacterium that causes food poisoning, Clostridium perfringens, and identified serine as an amino acid that inhibits spore ...

Early-Onset Colorectal Cancer Cases Surge Globally

Dec. 11, 2024 — Researchers show that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset ...

MRI Could Be Key to Understanding the Impact a Gluten Free Diet Has on People With Celiac Disease

Dec. 6, 2024 — Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with celiac disease, which could be the first step towards finding new ways of ...

All People Are Unique -- Also in the Gut

Dec. 2, 2024 — A new study increases our knowledge about the gut and the life of gut bacteria. The study shows, among other things, that changes in the gut environment have an impact on the composition and activity ...

Critical Relationship Between Stem Cells and Mechanical Signals Unveiled

Dec. 2, 2024 — Researchers uncover how two mechano-sensing ion channels are essential to maintain healthy stem ...

Deadly Diets Driving Digestive Diseases

Dec. 2, 2024 — Against the backdrop of an alarming increase in the number of people under 50 being diagnosed with bowel cancer, researchers are urging people to bump up their fiber intake and improve their eating ...

Food Additive Carrageenan (E 407) Could Disrupt the Intestinal Barrier and Increase the Risk of Type 2 Diabetes, Study Finds

Nov. 27, 2024 — The food additive carrageenan (E 407) can be responsible for the development of chronic inflammatory bowel disease, ulcers, and increased blood sugar levels in animals. Researchers have now ...

Researchers Find That Intestinal Infections Change Bile Composition

Nov. 26, 2024 — Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called ...

A Groundbreaking New Approach to Treating Chronic Abdominal Pain

Nov. 22, 2024 — A research team has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain. This groundbreaking innovation offers a safe, non-opioid-based solution for conditions ...