Pharmacology News

January 5, 2026

Top Headlines

Everyday Chemicals Are Quietly Damaging Beneficial Gut Bacteria

Jan. 5, 2026 A large study has revealed that dozens of widely used chemicals can damage beneficial gut bacteria. Many of these substances, found in pesticides and everyday industrial products, were never thought to affect living organisms at all. When gut ...

Scientists Find a Safer Way to Make Cells Burn More Calories

Jan. 5, 2026 Researchers have developed experimental compounds that make cells burn more calories by subtly tweaking how mitochondria produce energy. Older versions of these chemicals were once used for weight loss—but were banned for being deadly. The new ...

New Antibiotic Pill Shows Promise Against Drug-resistant Gonorrhea

Jan. 3, 2026 A one-dose oral drug called zoliflodacin has proven highly effective against gonorrhoea in a major international trial. The pill matched the success of current treatments while avoiding injections and complex dosing. As antibiotic resistance ...

Diabetes Drugs May Be Changing Cancer in Surprising Ways

Jan. 2, 2026 Common diabetes drugs may do more than regulate blood sugar—they could also influence how cancers grow, spread, or slow down. Researchers are now unraveling how these medications affect immune function, inflammation, and tumor biology, with ...

A Key Alzheimer’s Gene Emerges in African American Brain Study

Jan. 1, 2026 Scientists studying Alzheimer’s in African Americans have uncovered a striking genetic clue that may cut across racial lines. In brain tissue from more than 200 donors, the gene ADAMTS2 was significantly more active in people with Alzheimer’s ...

Nearly 70% of U.S. Adults Could Now Be Classified as Obese

Dec. 31, 2025 A major update to how obesity is defined could push U.S. obesity rates to nearly 70%, according to a large new study. The change comes from adding waist and body fat measurements to BMI, capturing people who were previously considered healthy. Many ...

What Cannabis Really Does for Chronic Pain

Dec. 30, 2025 Cannabis products with higher THC levels may slightly reduce chronic pain, particularly nerve pain, according to a review of multiple clinical trials. The improvement was small and short-lived, while side effects were more common. Products with ...

ADHD Drugs Don’t Work the Way We Thought

Dec. 29, 2025 ADHD stimulants appear to work less by sharpening focus and more by waking up the brain. Brain scans revealed that these medications activate reward and alertness systems, helping children stay interested in tasks they would normally avoid. The ...

Mini Brains Reveal Clear Brain Signals of Schizophrenia and Bipolar Disorder

Dec. 28, 2025 Tiny lab-grown brains are offering an unprecedented look at how schizophrenia and bipolar disorder disrupt neural activity. Researchers found distinct electrical firing patterns that could identify ...

Stanford Scientists Uncover Why MRNA COVID Vaccines Can Trigger Heart Inflammation

Dec. 27, 2025 Stanford scientists have uncovered how mRNA COVID-19 vaccines can very rarely trigger heart inflammation in young men — and how that risk might be reduced. They found that the vaccines can spark a ...

A Rare Cancer-fighting Plant Compound Has Finally Been Decoded

Dec. 27, 2025 UBC Okanagan researchers have uncovered how plants create mitraphylline, a rare natural compound linked to anti-cancer effects. By identifying two key enzymes that shape and twist molecules into their final form, the team solved a puzzle that had ...

A Surprising Brain Cleanup Reduced Epileptic Seizures and Restored Memory

Dec. 25, 2025 A new study suggests temporal lobe epilepsy may be linked to early aging of certain brain cells. When researchers removed these aging cells in mice, seizures dropped, memory improved, and some animals avoided epilepsy altogether. The treatment used ...

Latest Headlines

updated 6:22am EST

Dec. 25, 2025 Tramadol, a popular opioid often seen as a “safer” painkiller, may not live up to its reputation. A large analysis of clinical trials found that while it does reduce chronic pain, the relief is ...

Your Roommate’s Genes May Be Shaping Your Gut Bacteria

Dec. 23, 2025 Scientists studying thousands of rats discovered that gut bacteria are shaped by both personal genetics and the genetics of social partners. Some genes promote certain microbes that can spread ...

MIT Scientists Strip Cancer of Its Sugar Shield

Dec. 23, 2025 Scientists at MIT and Stanford have unveiled a promising new way to help the immune system recognize and attack cancer cells more effectively. Their strategy targets a hidden “off switch” that ...

A New Drug Could Stop Alzheimer’s Before Memory Loss Begins

Dec. 22, 2025 New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early ...

Parkinson’s Breakthrough Changes What We Know About Dopamine

Dec. 22, 2025 A new study shows dopamine isn’t the brain’s movement “gas pedal” after all. Instead of setting speed or strength, it quietly enables movement in the background, much like oil in an engine. ...

A Traditional Brazilian Plant Shows Unexpected Strength Against Arthritis

Dec. 22, 2025 A Brazilian study has confirmed that Joseph’s Coat, a plant used for generations in folk medicine, can significantly reduce inflammation and arthritis symptoms in lab tests. Researchers observed ...

A New Way to Prevent Gum Disease Without Wiping out Good Bacteria

Dec. 16, 2025 Scientists are uncovering a surprising way to influence bacteria—not by killing them, but by changing how they communicate. Researchers studying oral bacteria found that disrupting chemical signals ...

Cannabis Compounds Show Unexpected Power Against Ovarian Cancer

Dec. 15, 2025 Scientists have discovered that key compounds from cannabis—CBD and THC—show surprisingly strong effects against ovarian cancer cells. Used together, they slow cell growth, reduce colony ...

Mayo Clinic Neurosurgeon Reveals 8 Back Pain Myths to Stop Believing

Dec. 15, 2025 Back pain is wrapped in persistent myths, but many are far from the truth. From misconceptions about heavy lifting and bed rest to confusion over posture, exercise, and surgery, Dr. Meghan Murphy ...

Stem Cell Pain Sponge Soaks Up Osteoarthritis Joint Pain and Protects Cartilage

Dec. 15, 2025 SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain ...

Ozempic May Offer a Surprising Bonus Benefit for Brain Health

Dec. 13, 2025 A new analysis suggests that people with type 2 diabetes who use GLP-1 medications like Ozempic, Trulicity or Victoza may be less likely to develop epilepsy than those taking DPP-4 inhibitors. ...

Low Dose Melanoma Treatment Delivers Dramatically Better Results

Dec. 8, 2025 Using less ipilimumab appears to make melanoma immunotherapy both safer and more effective, with dramatically better response and survival outcomes. The findings suggest that reducing side effects ...

Scientists Reveal the Real Benefits and Hidden Risks of Medical Cannabis

Dec. 12, 2025 A sweeping review of more than 2,500 studies reveals that despite booming public enthusiasm, cannabis has strong scientific support for only a few medical uses, leaving most popular claims—like ...

Fast Depression Relief? Nitrous Oxide Shows Remarkable Potential

Dec. 2, 2025 Nitrous oxide may offer quick, short-term relief for people with major depression, especially those who haven’t responded to standard medications. The meta-analysis found rapid improvements after a ...

Bird Flu’s Surprising Heat Tolerance Has Scientists Worried

Nov. 28, 2025 Researchers discovered why bird flu can survive temperatures that stop human flu in its tracks. A key gene, PB1, gives avian viruses the ability to replicate even at fever-level heat. Mice ...

Is Your Gut Being Poisoned? Scientists Reveal the Hidden Impact of Everyday Chemicals

Dec. 2, 2025 Researchers discovered that 168 common chemicals can disrupt the growth of beneficial gut bacteria, with some also promoting antibiotic resistance. Many of these substances—found in food, water, ...

Immune Cells Use a Surprising Trick to Heal Muscle Faster

Nov. 24, 2025 A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering ...

New Nasal Nanodrops Wipe out Brain Tumors in Mice

Nov. 22, 2025 A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach ...

Simple Amino Acid Supplement Greatly Reduces Alzheimer’s Damage

Nov. 21, 2025 Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered ...

A Drug Already in Trials May Stop Chemotherapy Nerve Damage

Nov. 21, 2025 Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept ...

A Tiny Enzyme May Hold the Key to Safer Pain Relief

Nov. 23, 2025 Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or ...

Garlic Mouthwash Shows Shockingly Strong Germ-Fighting Power

Dec. 8, 2025 Garlic extract is emerging as a surprisingly powerful contender to chlorhexidine, the long-standing “gold standard” in antimicrobial mouthwashes. A systematic review of clinical studies shows ...

A 70-Year-Old Pregnancy Drug Just Revealed a Hidden Weakness in Brain Cancer

Dec. 2, 2025 Researchers have solved the decades-old mystery behind how a common pregnancy drug lowers blood pressure. It turns out the medication blocks a fast-acting “oxygen alarm” inside cells. That same ...

Tiny Microneedle Patch Dramatically Improves Heart Attack Recovery

Nov. 21, 2025 Researchers created a dissolvable microneedle patch that delivers IL-4 directly to damaged heart tissue, jump-starting repair after a heart attack. The targeted approach shifts immune cells into a ...

Inflammation Turns Bone Marrow Into a Breeding Ground for Disease

Nov. 18, 2025 Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and ...

How to Keep Ozempic/Wegovy Weight Loss Without the Nausea

Nov. 18, 2025 Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments ...

Her Food Cravings Vanished on Mounjaro Then Roared Back

Dec. 8, 2025 Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity. Her obsessive thoughts about food disappeared as ...

Chronic Pain May Dramatically Raise Your Blood Pressure

Nov. 17, 2025 Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong ...

A Tiny Ancient Virus Reveals Secrets That Could Help Fight Superbugs

Nov. 17, 2025 Scientists mapped the Bas63 bacteriophage in unprecedented detail, uncovering how its tail machinery infects bacteria. The structure reveals rare whisker-collar features and distant evolutionary ties ...

Your Skin Has a Built-in Cancer Defense and Sunlight Turns It Off

Nov. 30, 2025 Scientists have uncovered how too much sunlight can flip a hidden switch inside skin cells that makes inflammation spiral out of control and increases the risk of cancer. Their research reveals that ...