Stem Cells News

June 13, 2025

Top Headlines

Researchers Develop Innovative Model to Study Sense of Smell

June 3, 2025 — Scientists at Tufts have created a powerful 3D model of nasal tissue that reveals surprising new insights into how our sense of smell regenerates and why it sometimes fades. Contrary to past assumptions, a supposedly inactive type of stem cell ...

Researchers Find Promise in a New Peptide Drug to Combat a Deadly Brain Cancer

May 29, 2025 — A lab-designed molecule developed and extensively studied could represent a breakthrough in slowing tumor recurrence in glioblastoma, an aggressive and deadly form of brain ...

Discovery Offers New Insights Into Skin Healing in Salmon

May 27, 2025 — Scientists have discovered cells in the skin of Atlantic salmon that offer new insights into how wounds heal, tissues regenerate, and cellular transitions support long-term skin ...

First Vascularized Model of Stem Cell Islet Cells

May 23, 2025 — Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based ...

Researchers Identify a Dual Origin of Cells Controlling Puberty and Reproduction

May 21, 2025 — Researchers have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather ...

'Barcodes' Written Into Our DNA Reveal How Blood Ages

May 21, 2025 — A study explains how age reshapes the blood system. In both humans and mice, a few stem cells out-compete their neighbors and gradually take over blood production. The loss of diversity results in a blood system that has a preference for producing ...

A Step Closer to the Confident Production of Blood Stem Cells for Regenerative Medicine

May 16, 2025 — Researchers have developed a method to confidently produce blood cell precursors from stem cells in mice, by activating a set of seven key genes in the laboratory. The team takes a step forward ...

New Stem Cell Model Sheds Light on Human Amniotic Sac Development

May 15, 2025 — Researchers have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization. This is the first model of amniotic sac development ...

Improved Model System Allows Researchers to Study Embryo Development

May 15, 2025 — Research improves upon a popular experimental model of mammal development and in doing so, reveals more of the inner workings of a critical period during the formation of an ...

Vaccines of the Future: Harnessing the Immune System for Long-Lasting Protection

May 7, 2025 — Scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for ...

Chimpanzee Stem Cells Offer New Insights Into Early Embryonic Development

Apr. 25, 2025 — Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found that the inhibition of a specific regulatory gene ...

Why Our Waistlines Expand in Middle Age: Stem Cells

Apr. 25, 2025 — It's no secret that our waistlines often expand in middle-age, but the problem isn't strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. ...

Latest Headlines

updated 11:59am EDT

Supercharged Mitochondria Spark Aging-Related Blood Disorders

Apr. 16, 2025 — Scientists have discovered how aging blood stem cells acquire mutations that give them a growth edge, creating fertile ground for the development of clonol hematopoiesis, a condition that ...

Reprogramming Cancer Cells to Treat an Aggressive Type of Leukemia

Apr. 16, 2025 — A new study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 ...

Metabolism Shapes Life

Apr. 16, 2025 — New research shows Glycolysis -- the process of converting sugar into energy -- plays a key role in early development. More than fuel, Glycolysis doesn't just power cells -- it helps steer them ...

Driving the CAR to Fight Acute Myeloid Leukemia

Apr. 11, 2025 — A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team ...

NK Cells Complexed With Bispecific Antibody Yield High Response Rates in Patients With Lymphoma

Apr. 4, 2025 — A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific ...

Drug-Delivering Aptamers Target Leukemia Stem Cells for One-Two Knockout Punch

Apr. 3, 2025 — Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, ...

How the Brain and Inner Ear Are Formed

Apr. 3, 2025 — Researchers have developed a method that shows how the nervous system and sensory organs are formed in an embryo. By labeling stem cells with a genetic 'barcode', they have been able to follow the ...

Target to Repair Injured Muscles Discovered

Mar. 26, 2025 — A team has discovered a possible therapeutic approach to repair injured muscles either from aging or degenerative muscle ...

'Switch' Allows Intestinal Cells to Regenerate After Injury

Mar. 25, 2025 — Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Nursery of the Blood: How Stem Cells Calm the Body's Immune Response

Mar. 21, 2025 — Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental ...

Scientists Use Cellular Programming to Mimic First Days of Embryonic Development

Mar. 20, 2025 — Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever ...

Shaping the Future of Diabetes Treatment With 3D Bioprinting Technology

Mar. 19, 2025 — An innovative platform replicates pancreatic functions, transforming diabetes ...

Specialized Blood Vessels and Nitric Oxide Found to Be Key to Stem Cell Survival and Immune Evasion

Mar. 12, 2025 — Scientists have made an important discovery about the relationship between hematopoietic stem cells (HSCs) and immune response evasion. Their findings show how certain HSCs have regulatory functions ...

Beneficial Genetic Changes Observed in Regular Blood Donors

Mar. 11, 2025 — Researchers have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences in the mutations that ...

FLIpping the Switch: Boosting Stem Cell Numbers for Therapies

Mar. 10, 2025 — A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study. The discovery could lead ...

When You Get Hurt Matters: Circadian Rhythms Affect Muscle Repair

Mar. 5, 2025 — The body's internal clock doesn't just dictate when we sleep -- it also determines how quickly our muscles heal. A new study in mice suggests that muscle injuries heal faster when they ...

How to Clear the Toxic Tau Protein That Can Lead to Alzheimer's and Related Diseases

Mar. 5, 2025 — The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of protein, which can contribute to Alzheimer's and related ...

Key Protein Identified for Understanding and Treating Alzheimer's Disease

Feb. 28, 2025 — Researchers have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represents a target for future ...

How Our Lungs Back Up the Bone Marrow to Make Our Blood

Feb. 27, 2025 — Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

Stem Cell Transplant Clears Clinical Safety Hurdle for the Treatment of Wet Age-Related Macular Degeneration

Feb. 27, 2025 — Wet AMD in its early stages can be treated with drugs to reduce the formation of new blood vessels, but this treatment is inefficient in cases where blood vessel formation is already in its advanced ...

Cell Connects: Breaking Barriers in Stem Cell Communication Through mRNA Transfer

Feb. 19, 2025 — Messenger RNA can travel between different types of stem cells through tunnel-like structures, as revealed by a new study. By studying interactions between mouse and human stem cells, they discovered ...

Disruption of a Single Amino Acid in a Cellular Protein Makes Breast Cancer Cells Behave Like Stem Cells

Feb. 11, 2025 — Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Uncovering How Developmental Genes Are Held in a Poised State

Feb. 6, 2025 — New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation ...

How Healthy Stem Cells Turn Into Oral Cancer

Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the ...

Breakthrough in Childhood Brain Cancer Research Could Heal Treatment-Resistant Tumors, Keep Them in Remission

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice. The novel drug CT-179 ...

Research Discovery Halts Childhood Brain Tumor Before It Forms

Feb. 4, 2025 — A research team has identified a critical event driving tumor growth in a type of medulloblastoma -- and a way to block ...

New Research Unlocks Key to Long-Lasting Immune Response in Cancer and Chronic Diseases

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to function effectively. ...

First Mouse With Two Male Parents to Reach Adulthood

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood. Their results ...

Immune Complex Shaves Stem Cells to Protect Against Cancer

Jan. 17, 2025 — A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

DNA Damage Can Last Unrepaired for Years, Changing Our View of Mutations

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...