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Genes News

December 11, 2025

Top Headlines

 

Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” leverage this sublethal signal to regrow. ...
Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes this protection, allowing harmful molecules to damage cell membranes and trigger early dementia. Mouse and cell studies showed ...
Researchers successfully implanted a genetically modified pig liver into a human, proving that such an organ can function for an extended period. The graft supported essential liver processes before complications required its removal. Although the ...
FGF19 triggers the brain to burn more energy and activate fat-burning cells, offering a potential new path for obesity treatments. The hormone enhances thermogenesis and reduces inflammation, but only when the sympathetic nervous system is active. ...
Scientists uncovered a surprising four-layer structure hidden inside the hippocampal CA1 region, one of the brain’s major centers for memory, navigation, and emotion. Using advanced RNA imaging techniques, the team mapped more than 330,000 genetic ...
Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages released by heart cells that naturally support ...
A surprising link between constipation and kidney decline led researchers to test lubiprostone, revealing that it can protect kidney function. The results point toward gut-based, mitochondria-boosting therapies as a promising new avenue for CKD ...
Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the earliest stages of embryonic development. These mosaic mutations often go undetected yet can still be passed on and cause ...
Researchers have found a small but powerful switch inside breast cancer cells that helps them survive stressful conditions. When this switch flips, the cells activate protective programs that make them tougher and faster-growing. The finding reveals ...
Scientists have found that common foods can contain hidden contaminants formed during cooking or through environmental exposure. A new testing method called QuEChERS helps identify these chemicals more quickly and with greater ease. The research ...
A high-speed “zap-and-freeze” method is giving scientists their clearest view yet of how brain cells send messages. By freezing tissue at the instant a signal fires, researchers revealed how synaptic vesicles behave in both mouse and human ...
Researchers at UC Riverside have uncovered why soybean oil, one of America's most widely consumed ingredients, drives significant weight gain—at least in mice. The findings point not to the oil itself but to the fat-derived molecules it produces ...

Latest Headlines

updated 12:45am EST

Earlier Headlines

 

A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach ...

Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and ...

Scientists used CRISPR to disable the NRF2 gene, restoring chemotherapy sensitivity in lung cancer cells and slowing tumor growth. The technique worked even when only a fraction of tumor cells were ...

Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug ...

Scientists at Northwestern Medicine have developed a new genetic risk score that predicts who is most likely to experience irregular or dangerous heart rhythms. The test merges several types of ...

Researchers have uncovered that SerpinB3, typically linked to severe cancers, is also a key player in natural wound healing. The protein drives skin cell movement and tissue rebuilding, especially ...

Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, ...

Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, ...

Researchers have identified special immune cells in the brain that help slow Alzheimer’s. These microglia work to reduce inflammation and block the spread of harmful proteins. They appear to ...

Researchers discovered how rabies virus exerts massive control over host cells with very few genes. A key viral protein changes shape and binds RNA, allowing it to infiltrate different cellular ...

Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and ...

Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents ...

Scientists identified a small molecule that interrupts a harmful protein pair linked to diabetic inflammation and tissue damage. The compound helped wounds heal faster and reduced organ stress in ...

A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing ...

Penn State scientists uncovered an ancient bacterial defense where dormant viral DNA helps bacteria fight new viral threats. The enzyme PinQ flips bacterial genes to create protective proteins that ...

A newly identified disorder, MINA syndrome, results from a mutation in the NAMPT protein that deprives motor neurons of energy, leading to severe movement problems. The discovery not only deepens ...

UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s ...

Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it. ...

Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. Unlike ...

New research reveals that exercise counteracts the mood-damaging effects of a Western-style diet through specific gut and hormonal mechanisms. Running restored metabolites tied to mental well-being ...

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