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Scientists ID Compounds That Target Amyloid Fibrils in Alzheimer's, Other Brain Diseases
Scientists report an advance
toward "structure-based drug
design," with the potential
to delay or treat
Alzheimer's disease,
... > full story
Key Molecular Pathways Leading to Alzheimer's Identified
Key molecular pathways that
lead to late-onset
Alzheimer's disease have
been identified by
neuroscientists. The
findings present a new
... > full story
Shape-Shifting Disease Proteins May Explain Neurodegenerative Variation
Researchers have shown one
disease protein can morph
into different strains and
promote misfolding of other
disease proteins commonly
... > full story
New Way Discovered to Block Inflammation
Researchers have discovered
a mechanism that triggers
chronic inflammation in
Alzheimer's, atherosclerosis
and type-2 diabetes. The
results suggest a common
biochemical thread to
... > full story
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Necrostatin-1 Counteracts Aluminum's Neurotoxic Effects
August 2, 2013 — Researchers have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer's disease. A new study sheds light on the mechanism ... > full story -
New Drugs to Find the Right Target to Fight Alzheimer's Disease
August 2, 2013 — The future is looking good for drugs designed to combat Alzheimer's disease. Scientists have unveiled how two classes of drug compounds currently in clinical trials work to fight the disease. Their ... > full story -
Exercise May Be the Best Medicine for Alzheimer's Disease
July 30, 2013 — Regular, moderate exercise could improve memory and cognitive function in those at risk for Alzheimer's disease in a way no drug can. Scientists studied the effects of exercise on a group of older ... > full story -
Glucose Intolerance, Diabetes or Insulin Resistance Not Linked With Pathological Features of Alzheimer's Disease
July 29, 2013 — Glucose intolerance or insulin resistance do not appear to be associated with pathological features of Alzheimer disease (AD) or detection of the accumulation of the brain protein β-amyloid ... > full story -
Possible Blood Test for Alzheimer's Disease?
July 28, 2013 — A new blood test can be used to discriminate between people with Alzheimer's disease and healthy controls. It's hoped the test could one day be used to help diagnose the disease and other ... > full story -
Genetic Biomarker Detects Lewy Body Dementia
July 26, 2013 — Scientists have discovered the first genetic biomarker to detect Lewy body dementia (LBD), a disease that can be confused with Alzheimer's. This biomarker is found in 20% of cases and differentiates ... > full story -
Certain Blood Pressure Drugs Slow Dementia Deterioration
July 25, 2013 — A class of drug, called ACE inhibitors, which are used to lower blood pressure, slow the rate of cognitive decline typical of dementia, suggests new ... > full story -
Over 90 Percent of Dementia Cases in China Are Undetected, Study Finds
July 25, 2013 — An international team of researchers has found that over 90 percent of dementia cases in China go undetected, with a high level of undiagnosed dementia in rural ... > full story -
A Ginkgo Biloba Extract Promotes Proliferation of Endogenous Neural Stem Cells
July 23, 2013 — Neural stem cells proliferate in the subventricular zone and hippocampal dentate gyrus of adult mammals. However, the number of endogenous neural stem cells is insufficient to prevent cerebral ... > full story -
Early Detection and Treatment of Alzheimer's Disease Prevents Psychological and Behavioural Symptoms
July 18, 2013 — Persons with Alzheimer's disease are able to manage their everyday activities longer and they suffer from less psychological and behavioral symptoms if the diagnosis is made and treatment begun at a ... > full story
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