Crohn's Disease News

November 23, 2025

Top Headlines

A Drug Already in Trials May Stop Chemotherapy Nerve Damage

Nov. 21, 2025 Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept their nerves healthier. A drug already being ...

Inflammation Turns Bone Marrow Into a Breeding Ground for Disease

Nov. 19, 2025 Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and interferon-responsive T cells create a self-sustaining ...

How to Keep Ozempic/Wegovy Weight Loss Without the Nausea

Nov. 18, 2025 Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments that keep the benefits of weight loss while reducing ...

Chronic Pain May Dramatically Raise Your Blood Pressure

Nov. 17, 2025 Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong links between long-lasting pain, depression, ...

The Rarest Element on Earth Could Revolutionize Cancer Treatment

Nov. 11, 2025 Texas A&M scientists have unlocked new potential for astatine-211, a rare and short-lived element, as a highly precise cancer-fighting isotope. Its alpha emissions destroy tumor cells while sparing healthy tissue, making it ideal for targeted ...

The Hidden “Big Bang” That Decides How Bowel Cancer Grows

Nov. 7, 2025 Scientists have pinpointed a “Big Bang” moment in bowel cancer—when cells first evade the immune system. This early immune escape locks in how the cancer will behave as it grows. The discovery could help predict which patients respond to ...

Resetting the Body’s Rhythm Could Protect the Brain from Alzheimer’s

Nov. 1, 2025 Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced harmful tau buildup. The findings suggest that ...

MIT Discovers Amino Acid That Helps the Gut Heal Itself

Oct. 23, 2025 MIT scientists have found that an amino acid called cysteine can help the gut heal itself. In mouse studies, a cysteine-rich diet activated immune cells that release a molecule speeding up tissue repair in the small intestine. This process helped ...

Scientists Just Found a Molecule That Could Stop Parkinson’s in Its Tracks

Oct. 8, 2025 Researchers have designed a peptide that prevents the deadly misfolding of alpha-synuclein, the protein behind Parkinson’s and some dementias. In lab and animal tests, it stabilized the protein and ...

Cocoa Supplements Show Surprising Anti-aging Potential

Sep. 27, 2025 Daily cocoa extract supplements reduced key inflammation markers in older adults, pointing to a role in protecting the heart. The findings reinforce the value of flavanol-rich, plant-based foods for healthier ...

Scientists Uncover How to Block Pain Without Side Effects

Sep. 26, 2025 Scientists have discovered a way to block pain while still allowing the body’s natural healing to take place. Current painkillers like ibuprofen and aspirin often come with harmful side effects because they shut down both pain and inflammation. ...

Dementia-like Clumps Found in Cells Before Cancer Strikes

Sep. 22, 2025 Researchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so aggressively and why it is difficult to treat. By ...

Latest Headlines

updated 3:20pm EST

This Tiny Pill Could Change How We Diagnose Gut Health

Nov. 21, 2025 Tiny ingestible spheres filled with engineered bacteria can detect intestinal bleeding by glowing when they encounter heme. Early tests in mice suggest they could become a quick, noninvasive way to ...

A 25-Year Crohn’s Disease Mystery Finally Cracked by AI

Nov. 3, 2025 UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s ...

Exercise and Omega-3s Could Be the Secret to Healthier Teeth

Oct. 26, 2025 Researchers found that combining regular exercise with omega-3 supplements can make a big difference for oral health. The duo helps the immune system fight off chronic tooth root infections and ...

Exercise Might Be the Key to a Younger, Sharper Immune System

Oct. 14, 2025 Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

Scientists Finally Explain the Real Reason Pregnant Women Get Morning Sickness

Sep. 29, 2025 Morning sickness isn’t just random misery—it’s a biological defense system shaped by evolution to protect the fetus. By linking immune ...

Your Pancreas May Be Making Its Own Version of Ozempic

Sep. 21, 2025 Duke University scientists have discovered that pancreatic alpha cells, long believed to only produce glucagon, actually generate powerful amounts of GLP-1 — the same hormone mimicked by popular ...

Smoking’s Hidden Gut Bacteria Trick May Lead to New Colitis Treatments

Sep. 19, 2025 For decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates ...

Powerful New Painkiller ADRIANA Shows Promise in Ending Opioid Dependence

Sep. 2, 2025 Japanese scientists have developed ADRIANA, a non-opioid painkiller that could provide powerful relief without the dangers of addiction. With successful trials already completed, large U.S. studies ...

The Pandemic’s Secret Aftershock: Inside the Gut-Brain Breakdown

July 30, 2025 A new global study reveals a striking post-pandemic surge in gut-brain disorders like IBS and functional dyspepsia. Researchers compared data from 2017 and 2023 and discovered sharp increases IBS up ...

This Gut Hormone Could Explain 40% of IBS-D Cases—and Lead to a Cure

July 29, 2025 A mysterious gut hormone may be behind many cases of chronic diarrhea, especially in people with undiagnosed bile acid malabsorption, a condition often mistaken for irritable bowel syndrome. ...

Parkinson’s May Begin Decades Earlier — and Your Immune System Might Know First

June 27, 2025 Misbehaving T cells light up long before Parkinson’s symptoms show, zeroing in on vulnerable brain proteins. Their early surge could double as an alarm bell and a target for stop-it-early ...

How Brain Cells Meant to Help May Be Making Depression Worse

June 24, 2025 Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously ...

Combination Therapy Can Prolong Life in Severe Heart Disease

June 2, 2025 Aortic valve narrowing (aortic stenosis) with concomitant cardiac amyloidosis is a severe heart disease of old age that is associated with a high risk of death. Until now, treatment has consisted of ...

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic ...

Zika Virus Uses Cells' 'Self-Care' System to Turn Against Host

May 27, 2025 A new study reveals the biological secret to the Zika virus's infectious success: Zika uses host cells' own 'self-care' system of clearing away useless molecules to suppress the ...

New Factor Linked to Heart Failure

May 22, 2025 When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the ...

Unlocking the Secrets of Bat Immunity

May 21, 2025 Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease ...

Why Some Viral Infections Appear to Trigger Autoimmune Disease

May 20, 2025 By studying Chikungunya virus, scientists shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune ...

Maintaining Balance in the Immune System

May 19, 2025 Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and ...

Fast Food, Fast Impact: How Fatty Meals Rapidly Weaken Our Gut Defenses

May 19, 2025 A study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut ...

May 12, 2025 Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost ...

Colonic Inflammation Explains Missing Link Between Obesity and Beta-Cell Proliferation

May 9, 2025 How does obesity affect insulin production? Researchers are shining light on new stages of the ERK ...

MRI Breakthrough Could Revolutionize Diagnosis of Common Heart Problem Aortic Stenosis

May 8, 2025 Researchers have developed cutting-edge MRI technology to diagnose a common heart problem more quickly and accurately than ever before. Aortic stenosis is a progressive and potentially fatal ...

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 1, 2025 A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study introduced a ...

Lower Screening Age Calls for More Tailored Bowel Cancer Surveillance

Apr. 30, 2025 Australia's recent move to lower the starting age for bowel (colorectal) cancer screening from 50 down to 45 years old will mean better outcomes -- but it will also increase the burden on an ...

Hospitalized Patients Who Receive Alcohol Use Disorder Treatment Can Substantially Reduce Heavy Drinking

Apr. 21, 2025 A new study found that the oral and extended-release injectable forms of naltrexone are equally effective in helping patients consume less alcohol, suggesting that clinicians should integrate this ...

Existing Drug Has Potential for Immune Paralysis

Apr. 18, 2025 When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi. Researchers have demonstrated that an existing drug can ...

Early Mutations and Risk Factors for Stomach Cancer, and Develops a Pre-Cancer Model for Stomach Cancer Prevention

Apr. 16, 2025 Researchers have made significant advancements in understanding the earliest stages of stomach cancer, a leading cause of cancer-related deaths worldwide, through two recent innovative studies. With ...

Brain Pathway Links Inflammation to Loss of Motivation, Energy in Advanced Cancer

Apr. 10, 2025 Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that ...

Discovery Reveals Protein Involved in Parkinson's Disease Also Drives Skin Cancer

Apr. 9, 2025 A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new ...