Crohn's Disease News
July 30, 2015

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updated 10:54pm EDT

More Crohn's Disease News
July 30, 2015

'Biosimilars' for Children With IBD Need More Research

July 13, 2015 — Children with inflammatory bowel disease who are doing well on specific biological medications should not be switched to recently approved 'biosimilar' products, concludes an expert ... read more

Apr. 21, 2015 — Tumor necrosis factor (TNF), an immune system regulatory protein that promotes inflammation, also helps regulate sensitivity to bitter taste, new research has found. The finding may explain taste ... read more

Molecular Genetic Mechanisms Driving Breast Cancer Progression, Study Reveals

Apr. 3, 2015 — Researchers have uncovered how the body's inflammatory response can alter how estrogen promotes the growth of breast cancer cells. They have identified how a combination of signaling molecules ... read more

Female IBD Patients: Stay Up-to-Date on Your Cervical Cancer Screening

Mar. 26, 2015 — Women with inflammatory bowel disease may be at increased risk of cervical dysplasia and cancer, according to a new study. Although patients with both ulcerative colitis and Crohn's disease -- ... read more

Chronic Bowel Inflammation Is Diagnosed Too Late in Children, Adolescents

Mar. 17, 2015 — Cramping abdominal pains, diarrhea, bloody stools—these are common symptoms of chronic inflammatory bowel disease. Every year, thousands of children and adolescents develop the disease. But chronic ... read more

Mar. 17, 2015 — A new drug-like molecule that can halt inflammation has shown promise in preventing the progression of multiple sclerosis. Researchers developed the molecule inhibit a key signal that triggers ... read more

Insight Into Inflammatory Bowel Disease

Mar. 4, 2015 — The development of Inflammatory Bowel Disease (IBD) may be influenced through a protein in the gut leading to inflammation according to research. "These results provide further evidence to ... read more

Microbial Metabolite of Linoleic Acid Ameliorates Intestinal Inflammation

Feb. 18, 2015 — 10-hydroxy-cis-12-octadecenoic acid (HYA), a gut microbial metabolite of linoleic acid, has a suppressive effect on intestinal inflammation, researchers have discovered. HYA is expected to be ... read more

Feb. 16, 2015 — Cells lining the gut form a barrier that can be breached because of a signaling molecule called tumor necrosis factor (TNF). Elevated levels of TNF have been shown to cause inflammatory bowel ... read more

Partner Caregivers of Veterans With Traumatic-Brain Injuries May Be at Risk for Chronic Disease

Feb. 3, 2015 — Blame and anger associated with the grief of caring for a loved one with a traumatic-brain injury (TBI) may be related to inflammation and certain chronic diseases, according to ... read more

Feb. 2, 2015 — When cytotoxic T cells are activated, they produce TNF alpha that helps mediate immune responses. Scientists have now linked rising levels of TNF alpha in tumor tissue to increasing numbers of ... read more

Viruses May Play Unexpected Role in Inflammatory Bowel Diseases

Jan. 22, 2015 — Inflammatory bowel diseases are associated with a decrease in the diversity of bacteria in the gut, but a new study has linked the same illnesses to an increase in the diversity of ... read more

New Approach to Preventing Fibrosing Strictures in IBD

Jan. 15, 2015 — A natural protein made by immune cells may limit fibrosis and scarring in colitis, according to research. Fibrosing strictures that can obstruct the intestines are a major complication of ... read more

Dec. 16, 2014 — People's genes may have an influence over some of the intestinal bacteria that cause Crohn's disease and ulcerative colitis, collectively know as inflammatory bowel disease, a new study by ... read more

High Incidence of Bowel Disease Seen in People With Lung Conditions

Nov. 19, 2014 — People with airway diseases, including asthma and chronic obstructive pulmonary disease (COPD), have a higher incidence of inflammatory bowel disease, such as Crohn’s disease and ulcerative ... read more

TNF Inhibitors May Increase Cancer Risk in the Eye, Researchers Report

Nov. 17, 2014 — One of the family of drugs prescribed for rheumatoid arthritis and other inflammatory conditions is called tumor necrosis factor inhibitors. They act by dampening part of the immune system called ... read more

Blood Interferon Levels May Predict Response to TNF-Alpha Treatment in Rheumatoid Arthritis

Nov. 16, 2014 — Baseline levels of serum interferon in rheumatoid arthritis patients may help rheumatologists determine who will have a poor response to tumor necrosis factor-alpha inhibitor drugs, and one day help ... read more

Flu Infection Has Long-Ranging Effects

Nov. 3, 2014 — Flu infection has long-ranging effects beyond the lung that can wreak havoc in the gut and cause gastrointestinal symptoms, according to new research. The study suggests ways to relieve these ... read more

New Clinical Trial Data: Multiple Sclerosis Drug Candidate Also Shows Promise for Ulcerative Colitis

Oct. 28, 2014 — Positive new clinical data have been released on a drug candidate for ulcerative colitis. In the study, 199 patients with active, moderate to severe disease, the drug candidate RPC1063 has potential ... read more

Added Benefit of Vedolizumab Is Not Proven

Oct. 23, 2014 — In its dossier, the drug manufacturer of vedolizumab presented no suitable data for the therapeutic indication Crohn's disease or for ulcerative colitis, investigators ... read more

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