Epigenetics News

September 27, 2023

Top Headlines

Study Illuminates Mechanism That Annotates Genetic Information Passed from Fathers to Offspring

Sep. 6, 2023 — Scientists have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring. The findings shed new light on genomic imprinting, a ...

Epigenetic Mechanism That Causes Bitter Taste Distortion Discovered

Aug. 24, 2023 — A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune ...

Researchers Discover Potential Target for Gastric Cancers Associated With Epstein-Barr Virus

Aug. 22, 2023 — Scientists have discovered a potential target for gastric cancers associated with Epstein-Barr ...

Immune Memory Is Achieved by Epigenetic and Topological Rearrangements of DNA in Immune Cells

July 11, 2023 — A team of researchers has discovered that the memory of the immune system relies on characteristic epigenetic features and a specific 3D arrangement of the DNA in the nucleus of memory cells, ...

Latest Headlines

updated 11:01pm EDT

Unexpected Link Between Chromosomal Instability and Epigenetic Alterations

June 7, 2023 — New research finds an unexpected link between chromosomal instability and epigenetic alternations, both of which are hallmarks of cancer -- especially advanced, drug-resistant ...

Epigenetic Landscape Modulates Pioneer Transcription Factor Binding

May 24, 2023 — Scientists studied how the epigenetic landscape influences the binding of pioneer transcription factors, affecting access to ...

Impact of Maternal Stress During Pregnancy on Child's Health

Apr. 20, 2023 — New research examines the impact that maternal stress during pregnancy has on the neuro-development of ...

Researchers Discover Two Subtypes of Insulin-Producing Cells

Mar. 28, 2023 — A team of scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 ...

Small Differences in Mom's Behavior May Show Up in Child's Epigenome

Mar. 2, 2023 — Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response. Epigenetics are ...

New Study Unveils Epigenetic 'Traffic Lights' Controlling Stop and Go for Gene Activity

Mar. 1, 2023 — A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by ...

How Sex Differences Influence Lung Injury in Mice

Jan. 12, 2023 — More than 2,500 genes exhibit significant sex differences in expression in mouse alveolar type II cells (AT2s), important for keeping the lungs functioning, potentially explaining sex biases in the ...

Epigenetics Breaks Into the Clinical Practice of Cancer

Dec. 22, 2022 — Researchers describe the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new ...

Twin Study Links Exercise to Beneficial Epigenetic Changes

Dec. 6, 2022 — Consistent exercise can change not just waistlines but the very molecules in the human body that influence how genes behave, a new study of twins indicates. The study found that the more physically ...

HUSHing Repetitive-Like Elements Contributes to Normal Brain Development and Function

Nov. 4, 2022 — The gene-silencing complex HUSH might be involved in complex disorders affecting the brain and neurons. However, its mechanism of action remains ...

Earlier Headlines

Summaries
Headlines

The Guardian of the (Epi-)genome

Nov. 2, 2022 — Toxicologists have found that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their ...

'Kipferl': Guiding the Defense Against Jumping Genes

Oct. 4, 2022 — Researchers describe how different types of repetitive DNA elements are controlled by the same silencing mechanism in fruit fly ovaries. Central to their findings is an uncharacterized protein that ...

New Epigenetic Markers for Prostate Cancer Discovered

Oct. 3, 2022 — New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been ...

Scientists Propose That Obesity Is a Neurodevelopmental Disorder

Sep. 29, 2022 — A team of researchers reports that molecular mechanisms of brain development during early life are likely a major determinant of obesity ...

New Study Shows Transmission of Epigenetic Memory Across Multiple Generations

Sep. 26, 2022 — Changing the epigenetic marks on chromosomes leads to altered gene expression in offspring and in grandoffspring, demonstrating 'transgenerational epigenetic inheritance.' Without altering ...

How Many Drinks Is Too Many?

Sep. 12, 2022 — A new rodent study shows that even small quantities of alcohol can trigger epigenomic and transciptomic changes in brain circuitry in an area that is crucial in the development of ...

Using Nanopores to Detect Epigenetic Changes Faster

Aug. 31, 2022 — Changes known as epigenetic modifications play an important role in cancer development, among other things. Being able to analyze them quickly and reliably could, for example, contribute ...

Not All in the Genes: Are We Inheriting More Than We Think?

Aug. 11, 2022 — A fundamental discovery about a driver of healthy development in embryos could rewrite our understanding of what can be inherited from our parents and how their life experiences may shape ...

New Method Boosts the Study of Regulation of Gene Activity

July 1, 2022 — Researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously. Their method, called NT-seq, short for nitrite treatment followed by ...

Epigenetic Markers Predict Complications in Patients With Type 2 Diabetes

May 25, 2022 — A new study supports the notion that patients with type 2 diabetes patient should be divided into subgroups and given individualized treatment. The study demonstrates that there are distinct ...

How One of the X Chromosomes in Female Embryonic Stem Cells Is Silenced

May 19, 2022 — In most mammals, females have two X chromosomes and males have one X and one Y chromosome in each of their cells. To avoid a double dose of X-linked genes in females, one of the Xs is silenced early ...

An Epigenetic Cause of Miscarriages Is Identified and Cured in Mice

Apr. 27, 2022 — Researchers have discovered a gene responsible for prenatal death when critical epigenetic instructions are missing from egg cells. The study shows that in mice, failed epigenetic suppression of an ...

A Single Allele Deletion in Gene Encoding Zbtb38 Leads to Early Embryonic Death

Apr. 18, 2022 — Researchers have found that heterozygous loss of the methyl-CpG binding protein Zbtb38 downregulated the expression of the transcription factors Nanog and Sox2, as well as genes involved in epiblast ...

Epigenetic Regulator Explains Why Some Lung Cancer Patients Become Resistant to Common Therapeutics

Apr. 12, 2022 — Cellular biologists discover why some patients become resistant to standard treatments for nonsmall cell lung ...

Epigenetic Treatments: New Allies for Chemotherapies?

Apr. 11, 2022 — Though chemotherapies are effective in some patients, tumour cells may acquire tolerance to these treatments. In other words, cells adapt to chemotherapy so they can survive. A new study delivers ...

DNA Discovery Reveals a Critical 'Accordion Effect' for Switching Off Genes

Apr. 5, 2022 — Researchers have revealed how an 'accordion effect' is critical to switching off genes, in a study that transforms the fundamentals of what we know about gene silencing. The finding expands ...

DNA Methylation and Gene Expression in Children

Apr. 4, 2022 — A new study identifies associations between DNA methylation patterns and gene expression levels in blood samples from children. The findings provide researchers with a powerful tool to better ...

Learning from the Single Cell: A New Technique to Unravel Gene Regulation

Apr. 1, 2022 — How is the activity of genes regulated by the packaging of DNA? To answer this question, researchers developed a technique to measure both gene expression and DNA packaging at the same ...

How Accelerated Biological Aging May Cause Bowel Cancer

Mar. 29, 2022 — Scientists have shown how accelerated biological aging measured by an epigenetic clock may increase the risk of bowel cancer, according to a new ...

Bone Marrow Cancer: Potential Drug Targets

Mar. 17, 2022 — New research finds that patients with ASXL1-mutant chronic myelomonocytic leukemia -- an uncommon type of cancer of the bone marrow -- have distinctive epigenetic changes that can activate harmful ...

Wednesday, November 2, 2022