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Epigenetics News
February 26, 2017

Latest Headlines
updated 7:32am EST

More Epigenetics News
February 26, 2017

Dec. 15, 2016 — The complex process regulating gene expression is often compared to following a recipe. Miss a genetic ingredient, or add it in the wrong order, and you could have a disaster on your ... read more

Dec. 15, 2016 — Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells. X-chromosome silencing is ... read more

Infections During Pregnancy Have a Negative Impact Upon Maternal Care, Can Trigger Depression in Child

Dec. 15, 2016 — A viral infection in a pregnant woman not only affects her subsequent ability to provide maternal care but can also trigger depression in her offspring, which can then even extend into the next ... read more

Rare Obesity Syndrome Therapeutic Target Identified

Dec. 13, 2016 — An enzyme deficiency in the brain is linked to Prader-Willi syndrome, a genetic condition that causes extreme hunger and severe obesity beginning in childhood, scientists have ... read more

Loss of ARID1A Protein Drives Onset, Progress of Colon Cancer

Dec. 12, 2016 — A team of scientists has developed a model system in mice that allows them to look closely at how a protein often mutated in human cancer exerts its tumor-silencing effects. The new findings shed ... read more

Nov. 28, 2016 — Why is heart growth beneficial in some circumstances but detrimental in others? Research has uncovered the molecular basis of dangerous cardiac growth (cardiac hypertrophy), pointing the way for the ... read more

Going Beyond Genetics Yields Clues to Challenging Childhood Brain Cancer

Nov. 23, 2016 — Changes in the epigenetics suggest a prognostic marker for childhood ependymomas and similarities with DIPG tumors, report ... read more

Nov. 17, 2016 — Those with both rare and common types of autism spectrum disorder share a similar set of epigenetic modifications in the brain, according to a study. More than 68% of individuals with different types ... read more

Key Protein Implicated in Negative Side Effects of Senescence

Oct. 31, 2016 — A protein that plays a critical role in the expression of cytokines and chemokines has been identified by researchers. They have noted that decreasing this protein suppresses the expression of these ... read more

Stability of Exhausted T Cells Limits Durability of Cancer Checkpoint Drugs

Oct. 27, 2016 — Reinvigorating exhausted T cells in mice using a PD-L1 blockade caused very few T memory cells to develop. After the blockade, re-invigorated T cells became re-exhausted if antigen from the virus ... read more

Oct. 26, 2016 — Researchers have demonstrated how deregulation of an epigenetic mechanism that is active only in the early phases of neurogenesis triggers the subsequent death of neural ... read more

Oct. 18, 2016 — Researchers studying reproductive science identified a network of proteins often linked to cancer as also important to male fertility and the birth of healthy offspring, according to a ... read more

New Treatment Approach for Leukemia Renders Cancer Genes Powerless

Oct. 12, 2016 — A targeted epigenetic approach for the treatment of aggressive forms of leukemia has been revealed by researchers. Acute myeloid leukemia (AML) refers to a group of disorders that are also known as ... read more

Insights Into the Development of Sperm and Egg Cell Precursors in the Embryo

Oct. 10, 2016 — Researchers have investigated the early stages of the development of cells called primordial germ cells and developed strategies to generate 'lookalike' cells in the lab. The generation of ... read more

Toxicoepigenetics: The Emerging Field Many Are Exploring Without Knowing It

Oct. 6, 2016 — Toxicologists who research health, exposure-related disease, and susceptibility are actually concurrently studying the consequences of epigenetic regulation, which is why an understanding of ... read more

Epigenetics Provides New Insights Into the Pathogenesis of Lymphoma

Oct. 5, 2016 — Cancer cells have a different DNA methylation pattern from that of healthy cells. These patterns can be used to explain tumor-specific deviations in gene expression and to identify biomarkers for the ... read more

Simulations Help Explain How Genomes Take Form of 3-D Chromosomes

Sep. 26, 2016 — Scientists trying to solve the ultimate puzzle -- the architecture of the human genome -- have snapped another piece into place. They have developed a model to explain one part of the mechanism, the ... read more

Researchers Find a Potential Signature of Cognitive Function in People Living With HIV

Sep. 20, 2016 — A unique epigenetic footprint has been found in specific types of immune cells from blood that can identify individuals with HIV that have a range of impairments in cognitive function. Reliable ... read more

Inherited Parental Methylation Shifts Over Time, May Have Functional Effects in the Brain and Other Tissues

Sep. 20, 2016 — Inherited methylation—a form of epigenetic regulation passed down from parents to offspring—is far more dynamic than previously thought and may contribute to changes in the brain and other ... read more

Researchers Solve a Mystery of Early Embryonic Development

Sep. 20, 2016 — A novel technique has been created to map specific chemical (or “epigenetic”) modifications made to the protein packaging of DNA using a small population of cells. Such epigenetic marks play a ... read more

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