Jan. 30, 2023 — Researchers have designed a microfluidic device, or 'spleen-on-a-chip,' that can model how the spleen's filters become clogged by sickled red blood cells, leading to a life-threatening ...
Nov. 11, 2021 — Studying mice, researchers have developed a method of stem cell transplantation that does not require radiation or chemotherapy. Instead, the strategy takes an immunotherapeutic approach, combining ...
Sep. 21, 2021 — A multifaceted microfluidic in vitro assay is helping to identify the role of hypoxia on red blood cell aging via the biomechanical pathways. It holds promise for investigating hypoxic effects on the ...
Aug. 6, 2021 — Pooled results from phase 3 clinical trials demonstrate that roxadustat is efficacious and may be comparable to placebo in studies done to date for treating anemia in patients with chronic kidney ...
July 1, 2021 — New research finds that certain factors, such as a history of severe pain episodes and coexisting organ conditions, increase the risk of severe COVID-19 illness, including hospitalization, in ...
June 3, 2021 — Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD ...
June 1, 2021 — Researchers have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and ...
May 6, 2021 — Scientists have developed a highly efficient method to address a major challenge in biology -- identifying the genetic 'switches' that regulate gene ...
Apr. 9, 2021 — For those who have sickle cell disease, there are only a few treatment options, which include bone marrow transplants, gene therapy or other treatments that address a subset of symptoms. Now, ...
Mar. 24, 2021 — Sickle cell disease is the most prevalent inherited blood disorder in the world, affecting 70,000 to 100,000 Americans. However, it is considered an orphan disease, meaning it impacts less than ...
Mar. 11, 2021 — A new study demonstrates that machine-learning strategies can be applied to routinely collected physiological data, such as heart rate and blood pressure, to provide clues about pain levels in people ...
Mar. 1, 2021 — A new review analyzes disparities in experience and treatment of sickle cell ...
Feb. 1, 2021 — Researchers have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that ...
Jan. 21, 2021 — A new article reports two patients appear to have been cured of beta thalassemia and sickle cell disease after their own genes were edited with CRISPR-Cas9 technology. The two researchers who ...
Oct. 12, 2020 — As public interest and expanded research in human genome editing grows, many questions remain about ethical, legal and social implications of the technology. People who are seriously ill may ...
