Amyotrophic Lateral Sclerosis News
May 25, 2016

Latest Headlines
updated 6:58am EDT

More Amyotrophic Lateral Sclerosis News
May 25, 2016

Second Gene Modifies Effect of Mutation in a Dog Model of ALS

May 16, 2016 — Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists have discovered a modifier gene that affects the risk of developing DM in ... read more

Loss of MHCI in Motor Neurons Leads to ALS Astrocyte Toxicity

Feb. 29, 2016 — Until recently, the role of astrocytes, glial cells that normally support motor neurons, in motor neuron death has been a mystery, but new research sheds light on molecular mechanisms responsible for ... read more

Speech Disorder Called Apraxia Can Progress to Neurodegenerative Disease

Feb. 14, 2016 — It may start with a simple word you can't pronounce. Your tongue and lips stumble, and gibberish comes out. Misspeaking might draw a chuckle from family and friends. But, then, it keeps ... read more

Research Discovers Potential New Therapeutic Target for ALS

Jan. 19, 2016 — New findings reveal another piece of the amyotrophic lateral sclerosis (ALS) puzzle. A research team identified a protein that can protect against the toxic degeneration of cells in diseases like ... read more

Jan. 19, 2016 — Proteins associated with cancer suppression and prevention of hypoxia have been identified by researchers as key players in the progression of amyotrophic lateral sclerosis ... read more

ALS Protein Dynamics Highlight Delicate Balance Between Self-Association and Aggregation

Jan. 6, 2016 — The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study. The study supports the emerging idea that protein ... read more

Study Opens New Door for ALS Drug Discovery

Dec. 28, 2015 — Researchers have discovered the first-ever evidence-based description of the neuronal protein clumps thought to be important in Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's ... read more

Possible New Explanation for ALS

Oct. 29, 2015 — Researchers are proposing a new way of understanding Amyotrophic Lateral Sclerosis (ALS), the devastating and incurable neurological disease. Their findings could be a major milestone on the path to ... read more

Oct. 12, 2015 — Inhibiting infants' tongue movements impedes their ability to distinguish between speech sounds, researchers have found. The study is the first to discover a direct link between infants' ... read more

Oct. 5, 2015 — It's the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, but until now scientists weren't sure how a specific gene caused these devastating diseases. ... read more

Oct. 1, 2015 — Scientists have discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS). The results ... read more

Sep. 24, 2015 — A research team has uncovered molecular changes that explain, at least in part, why motor neurons rather than others are affected by the illness. Unlike ALS and other neurodegenerative diseases, ... read more

New Hope for Lou: Unexplored Therapeutic Targets for ALS

Sep. 3, 2015 — No cures exist for amyotrophic lateral sclerosis (ALS), and the only approved therapy slows the progression by only a few months. A new study identifies a promising unexplored avenue of treatment for ... read more

Effect of Presymptomatic BMI, Dietary Intake, Alcohol on ALS

Aug. 17, 2015 — Presymptomatic patients with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) consumed more daily calories but had lower body-mass index (BMI) than those individuals without ALS in a ... read more

Neurons' Broken Machinery Piles Up in ALS

Aug. 12, 2015 — Researchers have learned how a mutation in the gene for superoxide dismutase 1, which causes ALS, leads cells to accumulate damaged materials. The study suggests a potential target for treating this ... read more

Aug. 6, 2015 — Autopsies of nearly every patient with the lethal neurodegenerative disorder amyotrophic lateral sclerosis (ALS), and many with frontotemporal dementia (FTD), show pathologists telltale clumps of a ... read more

Aug. 6, 2015 — Researchers have developed a new model to study motor neuron degeneration and have used this to identify three genes involved in the neurodegeneration process. These findings could have relevance for ... read more

July 20, 2015 — Key differences between patients with sporadic amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and those with the most common genetic form of ALS, a mutation in the C9orf72 gene have ... read more

Uncovering a Key Relationship in ALS

July 15, 2015 — Novel antibodies for tracking C9orf72 have been developed by researchers, uncovering a link between genetic cause of ALS and its pathology. ALS is arguable humanity's most puzzling, intractable ... read more

New Light Shed on How Neurons Control Muscle Movement

June 23, 2015 — Researchers studying how the brain controls movement in people with paralysis, related to their diagnosis of Lou Gehrig's disease, have found that groups of neurons work together, firing in ... read more

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