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Amyotrophic Lateral Sclerosis News
February 19, 2017

Latest Headlines
updated 7:28am EST

More Amyotrophic Lateral Sclerosis News
February 19, 2017

Feb. 17, 2017 — Nonsense-mediated RNA decay (NMD) is a processing pathway in cells that, like a broom, cleans up erroneous RNA. Biomedical scientists report that they have come up with a method in the lab that ... read more

Children of Patients With C9orf72 Mutations Are at a Greater Risk of Frontotemporal Dementia or ALS at a Younger Age

Feb. 14, 2017 — The most common genetic cause of the brain diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is a mutation in the C9orf72 gene. Researchers have demonstrated that if an ... read more

Nov. 8, 2016 — Amyotrophic lateral sclerosis (ALS) is an adult onset, fatal neurodegenerative disease that selectively affects motor neurons. To date, more than 20 genes are identified as a causative of inherited ... read more

Aug. 18, 2016 — Structural biologists provide a new explanation for how ALS-associated genetic flaws interfere with the proper function and behavior of the protein ... read more

Scientists Keep a Molecule from Moving Inside Nerve Cells to Prevent Cell Death

Aug. 3, 2016 — A groundbreaking scientific study has found one way an RNA binding protein may contribute to ALS disease ... read more

New Gene Variants Present in Three Percent of All ALS Patients

July 25, 2016 — Variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial, making it ... read more

ALS Research Suggests Stem Cells Be 'Aged' to Speed Progress Toward Finding Treatments

July 19, 2016 — Scientists are seeking to build an improved stem-cell model of amyotrophic lateral sclerosis (ALS) to accelerate progress toward a cure for the devastating neurological disorder. Their findings ... read more

July 15, 2016 — Researchers have found evidence that bone marrow transplantation may one day be beneficial to a subset of amyotrophic lateral sclerosis.The data suggests the most common genetic mutation associated ... read more

Promising New Insights Into ALS

July 14, 2016 — Research into amyotrophic lateral sclerosis (ALS) has led to interesting and unexpected conclusions. When scientists were investigating the relevance of the higher expression of the IP3R2 protein in ... read more

Some Genetic Causes of ALS May Need an Epigenetic Trigger to Activate the Disease

July 5, 2016 — A new research report shows why, for some people, having a genetic predisposition to amyotrophic lateral sclerosis may not be enough to actually guarantee having the ... read more

Stem Cell Treatment for Lou Gehrig's Disease May Be Safe

June 29, 2016 — A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, suggests that transplanting human stem cells into the spinal cord may be done safely. While ... read more

Differences in How ALS Affects Eye, Limb Muscles Act as Clue

June 2, 2016 — In an effort to better understand what happens during Amyotrophic Lateral Sclerosis (ALS), researchers have compared the impact of ALS on the eye and limb muscles. They have focused on specific ... read more

Second Gene Modifies Effect of Mutation in a Dog Model of ALS

May 16, 2016 — Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists have discovered a modifier gene that affects the risk of developing DM in ... read more

Resistant Neurons Point the Way to Protective Factors in ALS

May 16, 2016 — The growth factor IGF-2 can prevent the death of human nerve cells in the incurable disease ALS, according to a new study. The work demonstrates that degeneration-resistant oculomotor neurons can be ... read more

Pesticide Exposure Linked to Increased Risk of ALS

May 9, 2016 — Survey data suggest reported cumulative pesticide exposure was associated with increased risk of amyotrophic lateral sclerosis (ALS), a progressive and fatal neurodegenerative disease, say ... read more

May 4, 2016 — Persons with the serious disorder ALS, can have a genetic mutation that causes the protein SOD1 to aggregate in motor neurons in the brain and spinal cord. Researchers at have discovered that, when ... read more

May 3, 2016 — When given to old rats, the drug, which is known to affect signaling by the neurotransmitter glutamate, reversed many age-related changes that occur in a brain region key to learning and memory. The ... read more

Unique Mouse Model for Studying ALS Developed

Apr. 21, 2016 — A unique mouse model has been developed that will allow researchers around the world to better study the genetic origins and potential treatments for a neurodegenerative brain disease that causes ... read more

Researchers Find That Immune Cells Play Unexpected Role in Lou Gehrig's Disease

Mar. 17, 2016 — Research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the ... read more

Mar. 16, 2016 — Following spinal cord injury, most patients experience an exaggeration of muscle tone called spasticity, which frequently leads to physical disability. A team has just identified one of the molecular ... read more

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