Amyotrophic Lateral Sclerosis News
July 25, 2016

Latest Headlines
updated 11:27am EDT

More Amyotrophic Lateral Sclerosis News
July 25, 2016

Second Gene Modifies Effect of Mutation in a Dog Model of ALS

May 16, 2016 — Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists have discovered a modifier gene that affects the risk of developing DM in ... read more

Unique Mouse Model for Studying ALS Developed

Apr. 21, 2016 — A unique mouse model has been developed that will allow researchers around the world to better study the genetic origins and potential treatments for a neurodegenerative brain disease that causes ... read more

Researchers Find That Immune Cells Play Unexpected Role in Lou Gehrig's Disease

Mar. 17, 2016 — Research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the ... read more

Mar. 16, 2016 — Following spinal cord injury, most patients experience an exaggeration of muscle tone called spasticity, which frequently leads to physical disability. A team has just identified one of the molecular ... read more

Loss of MHCI in Motor Neurons Leads to ALS Astrocyte Toxicity

Feb. 29, 2016 — Until recently, the role of astrocytes, glial cells that normally support motor neurons, in motor neuron death has been a mystery, but new research sheds light on molecular mechanisms responsible for ... read more

Speech Disorder Called Apraxia Can Progress to Neurodegenerative Disease

Feb. 14, 2016 — It may start with a simple word you can't pronounce. Your tongue and lips stumble, and gibberish comes out. Misspeaking might draw a chuckle from family and friends. But, then, it keeps ... read more

Important Role of Nucleocytoplasmic Transport in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Feb. 12, 2016 — Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders. No cure exists for these diseases. Ten percent of ALS patients ... read more

Feb. 5, 2016 — Children with Down syndrome who have motor speech deficits have been inadequately diagnosed, which could have a major impact on the interventions used by speech pathologists when treating patients, a ... read more

Targeting Upper Motor Neurons to Treat ALS

Feb. 1, 2016 — Scientists have demonstrated for the first time that it is possible to specifically modify gene expression in diseased upper motor neurons, brain cells that break down in ALS. The study provides ... read more

Research Discovers Potential New Therapeutic Target for ALS

Jan. 19, 2016 — New findings reveal another piece of the amyotrophic lateral sclerosis (ALS) puzzle. A research team identified a protein that can protect against the toxic degeneration of cells in diseases like ... read more

Jan. 19, 2016 — Proteins associated with cancer suppression and prevention of hypoxia have been identified by researchers as key players in the progression of amyotrophic lateral sclerosis ... read more

ALS Protein Dynamics Highlight Delicate Balance Between Self-Association and Aggregation

Jan. 6, 2016 — The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study. The study supports the emerging idea that protein ... read more

Study Opens New Door for ALS Drug Discovery

Dec. 28, 2015 — Researchers have discovered the first-ever evidence-based description of the neuronal protein clumps thought to be important in Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's ... read more

Possible New Explanation for ALS

Oct. 29, 2015 — Researchers are proposing a new way of understanding Amyotrophic Lateral Sclerosis (ALS), the devastating and incurable neurological disease. Their findings could be a major milestone on the path to ... read more

Oct. 12, 2015 — Inhibiting infants' tongue movements impedes their ability to distinguish between speech sounds, researchers have found. The study is the first to discover a direct link between infants' ... read more

Oct. 5, 2015 — It's the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, but until now scientists weren't sure how a specific gene caused these devastating diseases. ... read more

Oct. 1, 2015 — Scientists have discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS). The results ... read more

Sep. 24, 2015 — A research team has uncovered molecular changes that explain, at least in part, why motor neurons rather than others are affected by the illness. Unlike ALS and other neurodegenerative diseases, ... read more

New Hope for Lou: Unexplored Therapeutic Targets for ALS

Sep. 3, 2015 — No cures exist for amyotrophic lateral sclerosis (ALS), and the only approved therapy slows the progression by only a few months. A new study identifies a promising unexplored avenue of treatment for ... read more

Effect of Presymptomatic BMI, Dietary Intake, Alcohol on ALS

Aug. 17, 2015 — Presymptomatic patients with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) consumed more daily calories but had lower body-mass index (BMI) than those individuals without ALS in a ... read more

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