Joint Pain News

April 30, 2025

Top Headlines

The Antibiotic That Takes the Bite out of Lyme

Apr. 23, 2025 — Piperacillin, an antibiotic in the same class as penicillin, effectively cured mice of Lyme disease at 100-times less than the effective dose of doxycycline, the current gold standard treatment. At such a low dose, piperacillin also had the added ...

Post-Treatment Lyme Disease Syndrome May Be Driven by Remnants of Infection

Apr. 23, 2025 — Scientists believe they know what causes the treated infection to mimic chronic illness: the body may be responding to remnants of the bacteria that causes Lyme that tend to pool in the liver and joint ...

FDA Clears IND for Clinical Trial Testing Switchable CAR-T Therapy in Patients With Autoimmune Diseases, Without Chemotherapy

Apr. 9, 2025 — FDA has cleared an investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions. Patient ...

Researchers Discover Achilles Heel of Lyme Disease Pathogen

Mar. 20, 2025 — Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, and most likely other tick-borne diseases as ...

Latest Headlines

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Cannabis Terpenes Offer Potential New Way to Treat Fibromyalgia Pain

Mar. 12, 2025 — A recently completed study found that certain terpenes in Cannabis sativa are effective at relieving post-surgical and fibromyalgia pain in preclinical ...

Promising Active Ingredient for Lupus Therapy

Mar. 12, 2025 — Lupus is an autoimmune disease where the body's immune system attacks its own tissues and organs, causing inflammation and damaging organs. A new study has now shown that the natural active ...

Chronic Diseases Misdiagnosed as Psychosomatic Can Lead to Long Term Damage to Physical and Mental Wellbeing, Study Finds

Mar. 3, 2025 — A 'chasm of misunderstanding and miscommunication' is often experienced between clinicians and patients, leading to autoimmune diseases such as lupus ...

Breakthrough Study Discovers Genetic Mutation Could Be Basis for Novel Treatment of Rheumatoid Arthritis

Feb. 27, 2025 — Research reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in ...

New Study Supports Caution Regarding Use of Steroids

Feb. 26, 2025 — A new study of more than 2,900 patients provides evidence that it's likely best to use as little corticosteroid medicine as possible when treating people who have lupus pericarditis, a common heart ...

Topical Mupirocin Lowers Lupus Inflammation

Jan. 29, 2025 — Systemic lupus erythematosus commonly presents as a rash. The rashes are caused by inflammation from the immune system fighting the ...

Researchers Identify Key Protein to Potentially Halt Autoimmune Diseases and Allergies

Jan. 21, 2025 — Researchers identified a key protein as a potential therapeutic target for stopping the body's immune system from mistakenly attacking itself, ...

Signals from the Gut Could Transform Rheumatoid Arthritis Treatment

Nov. 8, 2024 — Changes in the gut microbiome before rheumatoid arthritis is developed could provide a window of opportunity for preventative treatments, new research ...

Two Key Genes Identified Linking Rheumatoid Arthritis and Osteoporosis

Nov. 5, 2024 — Researchers employed analysis tools and machine learning algorithms to identify two genes linked to rheumatoid arthritis and osteoporosis that could serve as diagnostic tools and potential targets ...

The Couples Who Cope Together, Stay Together

Oct. 29, 2024 — A new study has lifted the lid on how couples living with rheumatoid arthritis cope with the debilitating disease finding that those who cope with problems together had less psychological distress ...

In the Northeast, 50% of Adult Ticks Carry Lyme Disease Carrying Bacteria

Jan. 17, 2025 — Across most of the Northeast, getting bitten by a blacklegged tick-- also called a deer tick -- is a risk during spring, summer, and fall. A new Dartmouth study, published in Parasites and Vectors, ...

Lyme Borreliosis: New Approach for Developing Targeted Therapy

Oct. 23, 2024 — Lyme borreliosis is the most common tick-borne infectious disease in Europe. Up to 70,000 new cases are estimated each year in Austria alone. The bacterial infection can cause lasting health problems ...

Hip Osteoarthritis: Head Gets in the Way of Recovery, Study Suggests

Oct. 8, 2024 — Muscle activation in people suffering from hip osteoarthritis might be a case of 'mind over matter', new research has shown. A recent study investigated muscle function in people with hip ...

Neoself-Antigens Induce Autoimmunity in Lupus

Sep. 13, 2024 — Researchers found that T cells recognize neoself-antigens -- abnormal, unfolded host proteins presented by major histocompatibility complex II (MHC-II) lacking the invariant chain -- as non-self ...

Anxiety and Depression Linked to Chronic Pain in Children

Sep. 9, 2024 — Young people with chronic pain are three times more likely than their peers to also have clinical anxiety or depression, a new review has ...

Shedding Light on How Oral Bacteria Can Aggravate Rheumatoid Arthritis

Sep. 5, 2024 — Clinical studies have shown that periodontal disease with Aggregatibacter actinomycetemcomitans can exacerbate symptoms of rheumatoid arthritis (RA), but the molecular mechanisms behind this remain ...

Shedding Light on How Oral Bacteria Can Aggravate Rheumatoid Arthritis

Tiny Killers: How Autoantibodies Attack the Heart in Lupus Patients

Aug. 20, 2024 — A team of researchers report that autoantibodies alone directly affect heart function in lupus ...

Scientists Map DNA of Lyme Disease Bacteria

Aug. 15, 2024 — Researchers have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ...

Surprising Mechanism of Lupus Kidney Damage Identified

Aug. 14, 2024 — A team defined key cells behind severe kidney damage in lupus. The research can inform future antibody ...

Immune Cell Regulator Discovery Could Lead to Treatments for Arthritis and Severe COVID

Aug. 14, 2024 — The discovery of a new regulator affecting immune cells could lead to new treatments to reduce inflammation in diseases including arthritis and severe ...

Scientists Discover a Cause of Lupus and a Possible Way to Reverse It

July 10, 2024 — Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect may potentially reverse ...

Mobile App Therapy Leads to Significant Improvement in Fibromyalgia Management

July 8, 2024 — Research found a self-guided smartphone-based behavioral therapy led to significant improvements for patients with ...

New Insights Into T and B Cells Offer Hope for Autoimmune Disease Sufferers

June 4, 2024 — Scientists should focus on the interactions between T and B cells to find better treatments for autoimmune disorders, such as rheumatoid arthritis, according to a new ...

Tracking Down the Genetic Causes of Lupus to Personalize Treatment

May 23, 2024 — Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these ...

'I Feel Like I'm Alice in Wonderland': Why Nightmares and 'Daymares' Could Be Early Warning Signs of Autoimmune Disease

May 20, 2024 — An increase in nightmares and hallucinations -- or 'daymares' -- could herald the onset of autoimmune diseases such as ...

New Study Shows Certain Combinations of Antiviral Proteins Are Responsible for Lupus Symptoms and Affect Treatment Outcomes

May 13, 2024 — Researchers say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which affects up to 1.5 million Americans. The ...

Potential New Treatment Path for Lasting Lyme Disease Symptoms

Apr. 18, 2024 — Researchers have identified a potential new treatment for persistent neurological symptoms of Lyme disease, commonly seen even after antibiotic use. The study found that fibroblast growth factor ...

Gene Discovery Offers New Hope for People Living With Chronic Skin Disease

Mar. 25, 2024 — Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. ...

Clinical Trial Shows Rheumatoid Arthritis Drug Could Prevent Disease

Feb. 13, 2024 — A drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at ...