Lymphoma News
June 13, 2025
Top Headlines
May 28, 2025 — A team identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell ...
May 15, 2025 — Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of non-Hodgkin's lymphomas and is a rare but aggressive form ...
May 7, 2025 — A phase I study of a next-generation CAR T cell therapy showed a 52 percent complete remission rate for patients with relapsed/refractory ...
May 1, 2025 — Study data reveal how a specific sequence of cancer therapies can improve outcomes for patients with hard-to-treat ...
Apr. 29, 2025 — A Phase I trial involving ten patients with relapsed or refractory classical Hodgkin lymphoma or T-cell lymphoma has achieved a 100% overall response rate and a 50% complete remission rate, in ...
Apr. 4, 2025 — A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates ...
Apr. 1, 2025 — A new article outlines a new tool that measures blood inflammation as a marker for poor CAR T therapy ...
Mar. 3, 2025 — Research has shown that tattoo ink does not just remain where it is injected. Particles from the ink can migrate to the lymph nodes, where they ...
Feb. 21, 2025 — Researchers have discovered and analysed a rare but serious side effect of an innovative form of blood cancer ...
Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells fight cancer more effectively. These findings ...
Jan. 10, 2025 — A look at cancer cells: Thanks to an innovative method of super-resolution microscopy, researchers observed with molecular resolution in 3D how therapeutic antibodies attack and alter B cells, thereby inducing their destruction. Their research ...
Dec. 5, 2024 — An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer ...
Latest Headlines
updated 11:47am EDT
Mar. 25, 2025 — Even with significant expansion in the global market for antibodies used in clinical care and research, scientists recognize that there is still untapped potential for finding new antibodies. Many ...
Nov. 12, 2024 — These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines. ...
Oct. 23, 2024 — What keeps some immune systems youthful and effective in warding off age-related diseases? In new research done on mice, scientists point the finger at a small subset of blood stem cells, which make ...
Oct. 17, 2024 — Researchers discovered they could boost survival to 92% for patients with advanced Hodgkin lymphoma by adding the immunotherapy nivolumab to a current treatment regimen. This is compared to 83% ...
July 22, 2024 — The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found ...
July 10, 2024 — CAR-T cell therapy helps some with intractable lymphoma, but those who relapse have few options. Modifying the therapy's molecular target improved ...
June 20, 2024 — Research scientists found that a 'one-two punch' of combining the immunosuppressive drug ruxolitinib with existing checkpoint inhibitor therapies may be a more effective way to fight some cancers, ...
June 19, 2024 — Researchers have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma ...
June 18, 2024 — Researchers have discovered a molecular mechanism whose genetic disruption boosts the growth of the most common type of ...
June 12, 2024 — A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights ...
Earlier Headlines
Jan. 17, 2025 — A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...
June 12, 2024 — In April, the FDA warned of risk of secondary cancers in people receiving CAR-T cell therapy. A large study now finds the risk is low and not related to the CAR-T ...
June 12, 2024 — CAR-T cell therapies are transforming the treatment of previously incurable blood cancers, but a large proportion of patients still responds only poorly or not at all to them, calling for new ...
May 24, 2024 — A new study from Sweden suggests that tattoos could be a risk factor for cancer in the lymphatic system, or lymphoma. Now, the researchers underline the need for more research on the ...
May 23, 2024 — The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent ...
Apr. 29, 2024 — A recently completed study indicates that circulatory protein levels can provide important information for increasingly accurate diagnoses and personalised care in patients with aggressive B-cell ...
Mar. 12, 2024 — Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments ...
Mar. 1, 2024 — Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective ...
Feb. 7, 2024 — Scientists may have found a way around the limitations of engineered T cells by borrowing a few tricks from cancer itself. By studying mutations in malignant T cells that cause lymphoma, they zeroed ...
Jan. 26, 2024 — Researchers describe how specific gene activity could potentially enhance immune cell production. The researchers wanted to understand the mechanism of why some hematopoietic stem cells produce more ...
Jan. 17, 2024 — Axi-cel CAR T targets the CD19 molecule on large B-cell lymphoma cells. The ZUMA-7 trial demonstrated that axi-cel reduced the risk of disease progression, the need for new therapy, or death by 60% ...
Jan. 13, 2024 — Researchers have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of ...
Dec. 11, 2023 — Circulating tumor DNA predicts recurrence and splits disease into two subgroups of Hodgkin lymphoma. New drug targets or changes in treatments may reduce ...
Dec. 10, 2023 — Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose ...
Nov. 16, 2023 — Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated. However, many patients develop resistance to ...
Nov. 6, 2023 — Men who are overweight or obese at age 18 have a higher risk of 17 different cancers later in life. This has been shown in a study at the University of Gothenburg. The research also describes how the ...
July 27, 2023 — In a promising form of immunotherapy known as CAR T-cell (chimeric antigen receptor) therapy, the patient's T cells are engineered to better recognize and attack antigens on the surface of ...
Mar. 23, 2023 — Scientists have discovered a mechanism that linked a leukemic mutation to varying potentials for disease development -- a discovery which could eventually lead to a way to identify patients with the ...
Mar. 17, 2023 — A new substance has proven useful for treating staphylococcus infections in people with skin lymphoma. This is good news for the patients, but also for the global threat of antibiotics ...
Feb. 13, 2023 — The most comprehensive study to date of the blood cancer, Hodgkin lymphoma, has provided fascinating insights into what tumour cells must do to survive. Researchers found that cancer cells use ...
Friday, January 17, 2025
Wednesday, June 12, 2024
- Risk of Secondary Cancers After CAR-T Cell Therapy Low, According to Large Study
- Boosting CAR-T Cell Therapies from Under the Skin