Sickle Cell Anemia News
June 13, 2025
Top Headlines
Apr. 4, 2025 — Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, ...
Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ...
Jan. 17, 2025 — A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual (left) shows a larger brain with more white matter ...
Sep. 12, 2024 — Researchers have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse human populations that ...
Sep. 9, 2024 — Sickle cell disease is a common genetic disorder characterized by periodic occurrences of pain which happen repeatedly through life. These episodes, referred to as a vaso-occlusive episodes, happen ...
July 31, 2024 — Researchers found a small molecule that increases fetal hemoglobin production in human blood stem cells and leads to fewer sickled red blood cells in mice, providing proof of principle for developing ...
July 25, 2024 — In a rigorous medical records study covering tens of thousands of patients, researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before ...
Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their findings enhance strong evidence of hydroxyurea's effectiveness and could ...
Nov. 16, 2023 — Researchers have discovered that 'cell competition' following gene therapy results in the accumulation of stem cells with genetic mutations which make them grow faster. Some of these genetic mutations have been previously seen at higher levels in ...
Nov. 14, 2023 — A team has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new means to study diseases, ranging from noncancerous ...
Aug. 30, 2023 — A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were ...
Aug. 9, 2023 — A study shows new steps toward more patients getting gene ...
Latest Headlines
updated 11:48am EDT
Jan. 30, 2025 — A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell ...
Sep. 20, 2024 — The incidence of stroke continues to increase for adults and children living with sickle cell disease (SCD) despite the Stroke Prevention Trial in ...
Sep. 19, 2024 — A research team has discovered a mechanism in which blood stem cells respond to acute, severe anemia, through lipoprotein metabolism modification. It has been known how immediate erythroid precursors ...
July 27, 2023 — In a step forward in the development of genetic medicines, researchers have developed a proof-of-concept model for delivering gene editing tools to ...
May 4, 2023 — A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is ...
Apr. 17, 2023 — Scientists showed how prime editing can correct mutations that cause sickle cell disease in a potentially curative ...
Mar. 16, 2023 — While research has long established disparities in health outcomes among individuals living with sickle cell disease (SCD), few studies have ...
Oct. 24, 2022 — Researchers are working to reveal potential threats to the efficacy of CRISPR/Cas9 gene editing, even when it appears to be working as ...
Oct. 12, 2022 — Scientists found the cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for ...
Earlier Headlines
Apr. 11, 2024 — A drug approved to treat pulmonary arterial hypertension may be effective at managing hypertension and end-organ damage in patients with sickle cell disease, according to a new study. An early phase ...
Jan. 30, 2023 — Researchers have designed a microfluidic device, or 'spleen-on-a-chip,' that can model how the spleen's filters become clogged by sickled red blood cells, leading to a life-threatening ...