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Alzheimer's Research News

May 21, 2026

Top Headlines

 

A newly identified enzyme called IDOL could become a major new target in the fight against Alzheimer’s disease. Researchers found that removing it from neurons sharply reduced amyloid plaques and improved key brain processes linked to resilience ...
A new nanotechnology treatment reversed Alzheimer’s symptoms in mice by restoring the brain’s natural cleanup system. The specially engineered nanoparticles helped clear toxic amyloid proteins from the brain and repair the blood-brain barrier, ...
Researchers have shown for the first time that malfunctioning mitochondria — the cell’s energy generators — may directly cause cognitive decline in neurodegenerative diseases. By creating a new tool that temporarily boosts mitochondrial ...
Cannabis use among older adults is rising fast, but today’s marijuana is far more potent than many people realize — and experts warn the risks may be underestimated. Stanford Medicine specialists ...
A huge long-term study found that drinking two to three cups of coffee a day was linked to a much lower risk of dementia, especially before age 75. Researchers say caffeine may help keep brain cells active while reducing inflammation and harmful ...
A new study suggests a surprisingly simple compound could help fight Alzheimer’s disease. Researchers found that arginine—an inexpensive amino acid already considered safe—can reduce the buildup of toxic amyloid proteins in the brain, a ...
Drugs designed to clear amyloid beta from the brain—once seen as a promising path to slowing Alzheimer’s—may not actually help patients in any meaningful way, according to a major review of over 20,000 participants. Even more concerning, they ...
Scientists have discovered a way to help the brain clean itself of harmful Alzheimer’s plaques by activating its own support cells. By increasing a protein called Sox9, researchers were able to boost the activity of astrocytes, star shaped cells ...
Scientists have uncovered a surprising link between simple body movement and brain health: every time you tighten your abdominal muscles—even slightly—your brain may gently sway inside your ...
Researchers have identified a new potential weapon against Alzheimer’s: blocking a protein called PTP1B. In mice, this approach boosted memory and helped brain immune cells clear harmful plaque buildup. Since PTP1B is also linked to diabetes and ...
A rare group of adults over 80, known as SuperAgers, are rewriting what we thought was possible for the aging brain. With memory abilities comparable to people decades younger, their brains either resist or withstand the damage typically linked to ...
Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward ...

Latest Headlines

updated 9:42am EDT

Earlier Headlines

 

Subtle changes in brain blood flow and oxygen use are closely linked to hallmark signs of Alzheimer’s, including amyloid plaques and memory-related brain shrinkage. Simple, noninvasive scans may ...

Scientists have created a blood test that can estimate when Alzheimer’s symptoms are likely to begin. By measuring a protein called p-tau217, the model predicts symptom onset within roughly three ...

A simple brain-training program that sharpens how quickly older adults process visual information may have a surprisingly powerful long-term payoff. In a major 20-year study of adults 65 and older, ...

Researchers have mapped the genetic risk of hemochromatosis across the UK and Ireland for the first time, uncovering striking hotspots in north-west Ireland and the Outer Hebrides. In some regions, ...

Researchers studying nearly 2 million older adults found that cerebral amyloid angiopathy sharply raises the risk of developing dementia. Within five years, people with the condition were far more ...

When the brain rests, it usually replays recent experiences to strengthen memory. Scientists found that in Alzheimer’s-like mice, this replay still occurs — but the signals are jumbled and poorly ...

A new genetic study suggests that obesity and high blood pressure may play a direct role in causing dementia, not just increasing the risk. By analyzing data from large populations in Denmark and the ...

Cannabis-based medicines have been widely promoted as a potential answer for people living with chronic nerve pain—but a major new review finds the evidence just isn’t there yet. After analyzing ...

A long-term study of older adults with moderate hearing loss found that hearing aids did not lead to better performance on memory or thinking tests, but the story did not end there. Over seven years, ...

A massive international brain study has revealed that memory decline with age isn’t driven by a single brain region or gene, but by widespread structural changes across the brain that build up over ...

Alzheimer’s may be driven far more by genetics than previously thought, with one gene playing an outsized role. Researchers found that up to nine in ten cases could be linked to the APOE gene — ...

Researchers have identified OTULIN, an immune-regulating enzyme, as a key trigger of tau buildup in the brain. When OTULIN was disabled, tau vanished from neurons and brain cells remained healthy. ...

A massive Swedish study tracking nearly 28,000 people for 25 years found an unexpected link between full-fat dairy and brain health. Among adults without a genetic risk for Alzheimer’s, eating more ...

Your daily rhythm may matter more for brain health than previously thought. Older adults with weaker, more disrupted activity patterns were far more likely to develop dementia than those with steady ...

Cannabis products with higher THC levels may slightly reduce chronic pain, particularly nerve pain, according to a review of multiple clinical trials. The improvement was small and short-lived, while ...

New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early ...

Eating full-fat cheese and cream may be associated with a lower risk of dementia, according to a large study that tracked people for more than 25 years. Those who consumed higher amounts of these ...

Scientists have discovered that key compounds from cannabis—CBD and THC—show surprisingly strong effects against ovarian cancer cells. Used together, they slow cell growth, reduce colony ...

New research shows that aging blood can accelerate Alzheimer’s-like changes in the brain, while younger blood may offer protection. In mouse experiments, older blood worsened memory performance and ...

Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes this protection, allowing harmful molecules to damage cell membranes and ...

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