Crohn's Disease News

June 19, 2025

Top Headlines

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 — Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases ...

Combination Therapy Can Prolong Life in Severe Heart Disease

June 2, 2025 — Aortic valve narrowing (aortic stenosis) with concomitant cardiac amyloidosis is a severe heart disease of old age that is associated with a high risk of death. Until now, treatment has consisted of valve replacement, while the deposits in the heart ...

Zika Virus Uses Cells' 'Self-Care' System to Turn Against Host

May 27, 2025 — A new study reveals the biological secret to the Zika virus's infectious success: Zika uses host cells' own 'self-care' system of clearing away useless molecules to suppress the host proteins that the virus has employed to get into those cells in ...

New Factor Linked to Heart Failure

May 26, 2025 — When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the activity of this vital organ. It is often a reversible ...

Unlocking the Secrets of Bat Immunity

May 21, 2025 — Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses cause in humans, bats ...

Why Some Viral Infections Appear to Trigger Autoimmune Disease

May 20, 2025 — By studying Chikungunya virus, scientists shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune ...

Fast Food, Fast Impact: How Fatty Meals Rapidly Weaken Our Gut Defenses

May 19, 2025 — A study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut ...

Maintaining Balance in the Immune System

May 19, 2025 — Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and essential to preventing autoimmune disease. By the ...

May 13, 2025 — Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost ...

Colonic Inflammation Explains Missing Link Between Obesity and Beta-Cell Proliferation

May 9, 2025 — How does obesity affect insulin production? Researchers are shining light on new stages of the ERK ...

MRI Breakthrough Could Revolutionize Diagnosis of Common Heart Problem Aortic Stenosis

May 8, 2025 — Researchers have developed cutting-edge MRI technology to diagnose a common heart problem more quickly and accurately than ever before. Aortic stenosis is a progressive and potentially fatal ...

New Chronic Pain Therapy Retrains the Brain to Process Emotions

May 7, 2025 — Researchers have created an effective therapy for chronic pain that reduces pain intensity by focusing on emotional ...

Latest Headlines

updated 11:00am EDT

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 2, 2025 — A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease ...

Lower Screening Age Calls for More Tailored Bowel Cancer Surveillance

May 1, 2025 — Australia's recent move to lower the starting age for bowel (colorectal) cancer screening from 50 down to 45 years old will mean better outcomes -- but it will also increase the burden on an already ...

Hospitalized Patients Who Receive Alcohol Use Disorder Treatment Can Substantially Reduce Heavy Drinking

Apr. 22, 2025 — A new study found that the oral and extended-release injectable forms of naltrexone are equally effective in helping patients consume less alcohol, ...

Existing Drug Has Potential for Immune Paralysis

Apr. 19, 2025 — When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi. Researchers have demonstrated that an existing drug can ...

Early Mutations and Risk Factors for Stomach Cancer, and Develops a Pre-Cancer Model for Stomach Cancer Prevention

Apr. 16, 2025 — Researchers have made significant advancements in understanding the earliest stages of stomach cancer, a leading cause of cancer-related deaths ...

Brain Pathway Links Inflammation to Loss of Motivation, Energy in Advanced Cancer

Apr. 14, 2025 — Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a ...

Discovery Reveals Protein Involved in Parkinson's Disease Also Drives Skin Cancer

Apr. 11, 2025 — A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new ...

Mindfulness and Cognitive Behavioral Therapy Improve Chronic Low Back Pain

Apr. 7, 2025 — Eight weeks of mindfulness or cognitive behavioral therapy were associated with improved pain, physical function and quality of life and reduced daily opioid dose in adults with chronic low back pain ...

New Vaccine Concept Tackles Harmful Bacteria in the Intestine

Apr. 3, 2025 — In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning ...

Patient Navigators Improve Colonoscopy Rates After Abnormal Stool Tests, Study Shows

Apr. 2, 2025 — Timely follow-up colonoscopies can reduce the mortality rate from colorectal cancer, and patient navigators can play an important role in ...

Mini Rolling Robot Takes Virtual Biopsies

Mar. 26, 2025 — A tiny magnetic robot which can take 3D scans from deep within the body, that could revolutionize early cancer detection, has been developed by researchers. The team say this is the first time it has ...

Enzyme Engineering Opens Door to Novel Therapies for Parkinson's, Cancers and Other Hard-to-Target Protein Diseases

Mar. 26, 2025 — Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson's disease, and other serious illnesses. Now, ...

'Switch' Allows Intestinal Cells to Regenerate After Injury

Mar. 25, 2025 — Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Postpartum Female Preference for Cooler Temperatures Linked to Brain Changes

Mar. 25, 2025 — Mothers experience major metabolic adaptations during pregnancy and lactation to support the development and growth of the new life. Although many metabolic changes have been studied, body ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

How a Y Chromosome Gene May Shape the Course of Heart Valve Disease

Mar. 20, 2025 — Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and ...

Treating Chronic Inflammatory Diseases With JAK Inhibitors

Mar. 17, 2025 — Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. ...

Global Warming Can Lead to Inflammation in Human Airways, New Research Shows

Mar. 17, 2025 — In a recent, cross-institutional study partially funded by the National Institutes of Health, researchers report that healthy human airways are at higher risk for dehydration and inflammation when ...

Focus on the Gut-Liver Axis: Semisynthetic Bile Acid Has Anti-Inflammatory Effects on the Gut

Mar. 13, 2025 — A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

An Easy-to-Apply Gel Prevents Abdominal Adhesions in Animals

Mar. 12, 2025 — Up to 90% of abdominal surgeries result in adhesions -- abnormal scarring that ties together organs and tissues. A gel has now been shown to prevented adhesions in mice and ...

Worldwide Study Finds High Rates of Depression and Anxiety in People With Chronic Pain

Mar. 10, 2025 — A novel analysis of more than 375 published studies concluded that the association between chronic pain and rates of depression and anxiety is staggering. The study found that 40% of adults with ...

Gut Bacteria Heal the Colon

Mar. 10, 2025 — Scientists have uncovered how a gut bacterium, Clostridium scindens, aids in healing intestinal injuries by restoring bile acid balance. Their findings could pave the way for new treatments for ...

TB Vaccine Candidate Provides 'Elite' Protection

Mar. 5, 2025 — A live-attenuated tuberculosis (TB) vaccine candidate in development elicits a much more balanced and effective immune response compared to the existing vaccine used across much of the world, ...

Exercise and Healthy Eating Behavior Together Provide the Best Protection Against Cardiovascular Diseases

Mar. 5, 2025 — Researchers have found that women who exhibit disturbed eating behaviors and engage in low physical activity tend to have more central body fat and a higher risk of metabolic low-grade inflammation. ...

Possible Biomarker Identified for Crohn's Disease With Arthritis Type

Mar. 5, 2025 — People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a ...

School Absence Patterns Could ID Children With Chronic GI Disorders, Research Suggests

Mar. 4, 2025 — Children who frequently miss school because of abdominal complaints are far more likely to be suffering from chronic disorders such as irritable bowel syndrome than diseases that can be detected with ...

Synthetic Microbiome Therapy Suppresses Bacterial Infection Without Antibiotics

Mar. 3, 2025 — A synthetic microbiome therapy, tested in mice, holds promise as a new treatment for C. difficile, a notoriously difficult-to-treat bacterial infection, according to a team of researchers. The ...

New Insights Into How Gut Cells Respond to Bacterial Toxins

Feb. 25, 2025 — Researchers have found that specific gut cells, BEST4/CA7+ cells, regulate electrolyte and water balance in response to bacterial toxins that cause diarrhea. Their findings show that these cells ...

Dermatology Researchers Discover New Skin Disease Using Innovative Diagnostic Platform

Feb. 24, 2025 — Researchers described a new skin disease in a male patient with erythroderma, causing 80 percent of his skin to be covered with red, exfoliating skin lesions that itched and burned. After undergoing ...

New Drug May Reduce Need for Aortic Valve Surgeries by Slowing Disease Progression

Feb. 24, 2025 — Aortic valve stenosis (AVS) is a significant health concern affecting over 1.5 million Americans and millions more globally. Researchers are exploring the use of a new drug called ataciguat to manage ...