Personalized Medicine News

June 3, 2025

Top Headlines

South African Study Identifies Two New Breast Cancer Genes in Black Women

May 15, 2025 — South African scientists have identified two new breast cancer genes -- RAB27A and USP22 -- in Black women, marking the first GWAS of its kind on the continent. This breakthrough highlights the need for Africa-centred genomic research and tools to ...

Infant With Rare, Incurable Disease Is First to Successfully Receive Personalized Gene Therapy Treatment

May 15, 2025 — A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the ...

New Gene-Editing Therapy Shows Early Success in Fighting Advanced GI Cancers

May 2, 2025 — Researchers have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results show ...

Largest Osteoarthritis Genetic Study Uncovers Pathways to New Therapies and Repurposed Drugs

Apr. 28, 2025 — Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of ...

Latest Headlines

updated 10:45pm EDT

Why Common Leukemia Treatments Fail in Some Patients

May 21, 2025 — An international study has uncovered why a widely used treatment for acute myeloid leukemia (AML) doesn't work for everyone. The findings could help doctors better match patients with the therapies ...

Prostate Cancer Discovery Opens Door to More Tailored Treatments

Apr. 24, 2025 — Prostate cancer has distinct genetic properties in different groups of men that could be targeted to improve patient outcomes, new research ...

Common Genetic Variants Linked to Drug-Resistant Epilepsy

Apr. 15, 2025 — Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global ...

Osteoarthritis: Largest Genome-Wide Association Study Uncovers Drug Targets and Therapy Opportunities

Apr. 9, 2025 — Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally. Projections suggest ...

Researchers Develop New Way to Match Young Cancer Patients With the Right Drugs

Apr. 1, 2025 — A team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and ...

New AI Model Reveals Your True Biological Age from 5 Drops of Blood

Mar. 14, 2025 — A research team has developed a new system to estimate a person's biological age -- a measure of how well their body has aged, rather than just counting the years since birth. Using just five drops ...

Part of the Genetic Risk for Schizophrenia Acts Through the Placenta

Mar. 20, 2025 — An international team has identified associations between modifications in the placenta and the risk of developing schizophrenia, bipolar disorder, and major depression ...

A Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions

Mar. 17, 2025 — In the continuing evolution of personalized medicine, a new study has found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients ...

Prostate Cancer Is Not a Death Knell, Study Shows

Mar. 10, 2025 — Prostate cancer statistics can look scary: 34,250 U.S. deaths in 2024. 1.4 million new cases worldwide in 2022. ...

AI May Help Clinicians Personalize Treatment for Generalized Anxiety Disorder

Mar. 6, 2025 — Individuals with generalized anxiety disorder (GAD), a condition characterized by daily excessive worry lasting at least six months, have a high ...

Advanced Genetic Blueprint Could Unlock Precision Medicine

Mar. 4, 2025 — Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision ...

New Genetic Risk Score Identifies Individuals at Risk for Heart Disease Who May Benefit Most from Cholesterol-Lowering Therapies

Feb. 26, 2025 — Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world. Atherosclerosis, or the buildup of plaque in the ...

Discovery of Rare Gene Variants Provides Window Into Tailored Type 2 Diabetes Treatment

Feb. 26, 2025 — A new study details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people. The unusual finding is a step toward more ...

Hidden Genetic Causes of Congenital Heart Disease Identified

Feb. 20, 2025 — Scientists have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth ...

Almost 90% of People Would Agree to Genetic Testing to Tailor Medication Use, Survey Finds

Feb. 19, 2025 — New research shows almost 90% of people in England would agree to genetic testing to get the most effective medication and reduce the risk of side ...

Gene Therapy for Rare Epilepsy Shows Promise in Mice

Feb. 14, 2025 — Recent research takes aim at the a variant in gene SCN1B, which causes a severe form of developmental epileptic ...

AI Unlocks Genetic Clues to Personalize Cancer Treatment

Feb. 11, 2025 — A groundbreaking study has uncovered how specific genetic mutations influence cancer treatment outcomes -- insights that could help doctors tailor treatments more effectively. The largest study of ...

New Perspectives for Personalized Therapy of Brain Tumors

Feb. 11, 2025 — Scientists have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as ...

Personalized Cancer Treatment Using 3D Bioprinting Technology

Feb. 7, 2025 — Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of ...

Cancer Vaccine Shows Promise for Patients With Stage III and IV Kidney Cancer

Feb. 5, 2025 — Researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune ...

Artificial Intelligence Improves Personalized Cancer Treatment

Jan. 30, 2025 — Personalized medicine aims to tailor treatments to individual patients. Until now, this has been done using a small number of parameters to predict the course of a disease. However, these few ...

Inherited Gene Elevates Prostate Cancer Risk in Affected Families

Jan. 28, 2025 — The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new ...

Genetic 'Fingerprint' to Predict Drug Resistance in Bacteria

Jan. 28, 2025 — New research has identified a unique genetic signature in bacteria that can predict their likelihood of developing antibiotic resistance, a finding that can help quickly identify precision-based ...

Combination of Dual-Targeted Therapies and Chemotherapy Shows High Response Rates in BRAF-Mutated Metastatic Colorectal Cancer

Jan. 25, 2025 — Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefited from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy ...

Predicting How Childhood Kidney Cancers Develop

Jan. 23, 2025 — New research looked at how cancers arise in children who are predisposed to developing the childhood kidney cancer, Wilms tumor, which could help anticipate the development of tumors before they ...

Novel PET Approach Identifies Early Signs of Pulmonary Arterial Hypertension

Jan. 22, 2025 — A new molecular imaging technique -- 18F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker ...

How Your Brain Learns from Rewards Might Hold the Key to Treating Depression

Jan. 22, 2025 — Using computational models, the researchers studied how the brain's reward-learning system functions in those with depression, especially among individuals experiencing anhedonia, the inability ...

Monitoring Tumor-Informed Circulating Tumor DNA After CGP

Jan. 15, 2025 — A research team proposes a method to assess cancer patients for their likelihood to either respond to treatment or ...

SCP-Nano: A New Technology to Visualize Nanocarriers in Cells and Tissues

Jan. 14, 2025 — How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers have taken an important step to answer this question. ...

Scientists Identify Genes Driving Cancer Spread

Jan. 9, 2025 — Cancer metastasis -- the spread of cancer to other organs -- is the leading cause of death among cancer patients. Researchers have now uncovered a 'genetic signature' of 177 genes shared ...