Crohn's Disease News
August 27, 2016

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updated 12:55am EDT

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August 27, 2016

Research Brings New Understanding of Chronic Inflammatory Disease

July 6, 2016 — New light has been shed on the way cells tune in to different inflammatory signals to understand what is happening in the body, report life ... read more

New Research May Help to Develop Effective Pain Killers

June 30, 2016 — If you have ever chopped chilies and then accidentally touched your eyes you will be familiar with the burning sensation that this causes. However, the substance responsible for this sensation can ... read more

PET Detects Neuroinflammation in Multiple Sclerosis

June 13, 2016 — The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a ... read more

Biosimilar Switching Not Suitable for All Patients

June 9, 2016 — The results of a study showed that when antibodies develop in response to the biological treatment Remicade® (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: ... read more

New Mode of Action for HUMIRA in Rheumatoid Arthritis Patients

June 6, 2016 — Researchers have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid ... read more

Regulation of Semiochemicals in Inflammation

June 1, 2016 — A team of researchers has discovered a fundamental new mechanism. Tumor necrosis factor-alpha (TNF-?) is a central signalling substance of the immune system and involved in many inflammatory ... read more

Gut Flora May Lead to Better Diagnosis Tool for Liver Disease, Open Avenues for Treatment

May 23, 2016 — Primary sclerosing cholangitis is a liver disease with no effective medical treatment. Liver transplantation is the only proven long-term treatment of PSC. The vast majority of patients with PSC also ... read more

May 17, 2016 — The transcription factor hepatocyte nuclear factor 4-alpha (HNF4-alpha) plays a key role in colon cancer and colitis. HNF4-alpha comes in two major isoforms, P1 and P2, but how these are distributed ... read more

May 9, 2016 — By studying the interplay between genetic risk factors for Crohn's and the bacteria that populate the gut, researchers at have discovered a new potential cause for this disorder in some patients ... read more

Genetic Variants in Patients With Crohn's Disease Prevent 'Good' Gut Bacteria from Working

May 6, 2016 — A major type of inflammatory bowel disease may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new ... read more

Ozanimod as Effective in Treating Ulcerative Colitis, Study Shows

May 4, 2016 — Ozanimod, a novel drug molecule, is moderately effective in the treatment of ulcerative colitis, researchers have demonstrated. Ulcerative colits is a debilitating autoimmune disease that causes ... read more

Salt-Inducible Kinases May Have Therapeutic Potential for Autoimmune Diseases

Apr. 29, 2016 — A new research report suggests that specific enzymes, called 'salt-inducible kinases,' may be able to help curb runaway inflammation associated with autoimmune diseases like Crohn's ... read more

Minimally Invasive Colitis Screening Using Infrared Technology Could Offer Fast, Simple Test

Apr. 26, 2016 — A minimally invasive screening for ulcerative colitis, a debilitating gastrointestinal tract disorder, using emerging infrared technology could be a rapid and cost-effective method for detecting ... read more

Apr. 20, 2016 — TNF-alpha, a proinflammatory molecule and protein produced by the body's cells during infection, also promotes the immune system regulatory responses by first inducing immune surveillance cells. ... read more

Nanoparticles Show Promise for Treating Intestinal Inflammation, Study Finds

Apr. 7, 2016 — Nanoparticles designed to block a cell-surface molecule that plays a key role in inflammation could be a safe treatment for inflammatory bowel disease, according to ... read more

Mar. 16, 2016 — Intestinal inflammation in mice can be dampened by subjecting them briefly to a diet restricted in amino acids, the building blocks of proteins, researchers have ... read more

Crohn's Disease Diagnosis Difficult to Obtain, Life Altering, New National Study Finds

Mar. 1, 2016 — A new national survey of Crohn's disease patients reveals that it was not uncommon for patients to see multiple health-care professionals, have numerous office visits, and endure multiple ... read more

Autoimmune Diseases: Novel Drug for Arthritis

Feb. 29, 2016 — A significant step has been made in creating a new type of drug for treatment of autoimmune diseases, such as rheumatoid arthritis and Crohn's ... read more

Is Anti-TNF Therapy Safe for Inflammatory Bowel Disease Patients With Prior Cancer?

Feb. 29, 2016 — A previous history of cancer doesn't necessarily preclude treatment with antibodies against tumor necrosis factor (anti-TNF) for patients with inflammatory bowel diseases, suggests a new ... read more

How Does the Gut Microbiota Respond to Iron Replacement?

Feb. 17, 2016 — Iron deficiency is often an issue in patients with inflammatory bowel diseases. An international and interdisciplinary research group has now investigated how the intestinal microbiota responds to ... read more

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