Pharmaceuticals News

April 30, 2025

Top Headlines

Structure Dictates Effectiveness, Safety in Nanomedicine

Apr. 25, 2025 — Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue this precise control should be applied to optimize ...

Right Patient, Right Dose, Right Time

Apr. 24, 2025 — A new study uses AI to modify drug doses for personalized cancer ...

The Antibiotic That Takes the Bite out of Lyme

Apr. 23, 2025 — Piperacillin, an antibiotic in the same class as penicillin, effectively cured mice of Lyme disease at 100-times less than the effective dose of doxycycline, the current gold standard treatment. At such a low dose, piperacillin also had the added ...

Pulmonary Fibrosis Has No Cure: Could a Cancer Drug Hold the Answer?

Apr. 22, 2025 — Researchers have identified a potential new way to treat idiopathic pulmonary fibrosis (IPF), a deadly and currently incurable lung disease that affects more than 3 million people ...

Latest Headlines

updated 4:42pm EDT

Using Blue Light to Fight Drug-Resistant Infections

Apr. 22, 2025 — Researchers have made a breakthrough discovery that could potentially revolutionize treatments for antibiotic-resistant infections, cancer and other challenging gram-negative pathogens without ...

Older Adults Respond Well to Immunotherapy Despite Age-Related Immune System Differences

Apr. 21, 2025 — Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, ...

IV Medication Could Be Taken Orally for Range of Cancer, Alzheimer's Treatments

Apr. 21, 2025 — Breakthrough research could make any IV drug able to be taken orally for a range of hard-to-treat cancers and other diseases, and redefine how ...

Existing Drug Has Potential for Immune Paralysis

Apr. 18, 2025 — When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi. Researchers have demonstrated that an existing drug can ...

Scientists 'Hack' Cell Entry to Supercharge Cancer Drugs

Apr. 17, 2025 — Scientists could reshape cancer treatment by helping powerful drugs work better in the body by exploiting a surface protein called CD36 that helps pull substances into cells. This dramatically ...

Common Genetic Variants Linked to Drug-Resistant Epilepsy

Apr. 15, 2025 — Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global ...

Structural Images of a Tuberculosis-Fighting Virus

Apr. 16, 2025 — Mycobacteria are the world's most deadly bacteria --c ausing infectious diseases including tuberculosis (TB), which alone kills more than one million people each year. New drugs to fight these ...

Pharmacists' Communication Skills Lead to Reduced Drug Prescriptions by Doctors

Apr. 10, 2025 — Assertiveness -- a communication style that involves frank self-expression while respecting others -- is considered a teachable skill and has been ...

Researchers May Have Solved Decades-Old Mystery Behind Benzodiazepine Side Effects

Apr. 14, 2025 — Identifying a key protein's role could improve the common mental health medications and point to new treatments for inflammation-related diseases, a ...

LSD Analogue With Potential for Treating Schizophrenia Developed

Apr. 14, 2025 — Researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that harnesses the psychedelic's therapeutic power with reduced hallucinogenic ...

Brain Study Increases Understanding of What Triggers Drug Use Relapse

Apr. 10, 2025 — Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Study Provides Scaffold to Selectively Target Drug Breakdown Process

Apr. 10, 2025 — Scientists explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug ...

Researchers Use AI to Improve Diagnosis of Drug-Resistant Infections

Apr. 7, 2025 — Scientists have developed an artificial intelligence-based method to more accurately detect antibiotic resistance in deadly bacteria such as tuberculosis and staph. The breakthrough could lead to ...

Touchlessly Moving Cells: Biotech Automation and an Acoustically Levitating Diamond

Apr. 3, 2025 — Engineers have created new technology that can move cells without touching them, enabling critical tasks that currently require large pieces of lab equipment to be carried out on a benchtop ...

Drug-Delivering Aptamers Target Leukemia Stem Cells for One-Two Knockout Punch

Apr. 3, 2025 — Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

Successful Therapy Confirmed for Newborns With the Fatal Metabolic Disorder MoCD Type A

Apr. 3, 2025 — Early administration of the drug Fosdenopterin/rcPMP improves the chances of survival of infants with MoCD type A and promotes the development of brain ...

Antibiotic Resistance Among Key Bacterial Species Plateaus Over Time

Apr. 3, 2025 — Antibiotic resistance tends to stabilize over time, according to a new ...

Precision Medicine Could Be Possible in the Fight Against Antibiotic Resistance

Apr. 3, 2025 — Certain antibiotic-resistant infections could be treated with precision medicine in the future, thanks to a new resource mapping plasmids the ultimate vehicle of rapid bacterial ...

Some Gut Bacteria Could Make Certain Drugs Less Effective

Apr. 3, 2025 — A new study shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less ...

Researchers Develop New Way to Match Young Cancer Patients With the Right Drugs

Apr. 1, 2025 — A team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins. The team has combined these two ...

New Flexible Hydrogel Could Improve Drug Delivery for Post-Traumatic Osteoarthritis Treatment

Mar. 31, 2025 — Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms but do not prevent or stop the progression of the condition. ...

Could an Arthritis Drug Unlock Lasting Relief from Epilepsy and Seizures? Promising Results in Mice

Mar. 25, 2025 — A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers. If the drug proves viable for human patients, it would ...

Scientists Unlock Frogs' Antibacterial Secrets to Combat Superbugs

Mar. 25, 2025 — Engineers have derived potent new antibiotics from a frog's secretions. The new molecules demonstrated capabilities on par with existing last-resort antibiotics, without harming human cells or ...

New Non-Surgical Contraceptive Implant Is Delivered Through Tiny Needles

Mar. 24, 2025 — Investigators have developed a long-acting contraceptive implant that can be delivered through tiny needles to minimize patient discomfort and increase the likelihood of medication use. Their ...

Engineers Develop a Better Way to Deliver Long-Lasting Drugs

Mar. 24, 2025 — Engineers devised a way to deliver drugs such as contraceptives by injecting them as suspended crystals. Once under the skin, the crystals assemble into a drug depot that can last for months or ...

Groundbreaking Light-Driven Method to Create Key Drug Compounds

Mar. 21, 2025 — Scientists have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs interact with the ...

New Cannabis Formula Will Help Epilepsy, Multiple Sclerosis Sufferers

Mar. 19, 2025 — Scientists have come up with an innovative solution to improve the effectiveness of cannabidiol to treat epilepsy, multiple sclerosis and other neurodegenerative ...

Anti-Amyloid Drug Shows Signs of Preventing Alzheimer's Dementia

Mar. 19, 2025 — An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a new study. The ...

Team Finds Regional, Age-Related Trends in Exposure to Drug-Resistant Pathogen

Mar. 19, 2025 — Campylobacter infections are the most common foodborne illnesses in the U.S., sickening an estimated 1.5 million people each year. A new study examined records of Campylobacter jejuni infections from ...

Stroke Rehabilitation Drug Repairs Brain Damage

Mar. 18, 2025 — A new study has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice, following from human ...